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Small vesicles released by intestinal bacteria induce immune activation and progression of liver cirrhosis

Researchers from Niigata University and Kyoto Prefectural University have revealed that small vesicles, around 100 nm in size, released by intestinal bacteria induce immune activation and progression of liver cirrhosis, as well as reduction of serum albumin level, subsequently leading to edema and ascites. ....

Atsunori Tsuchiya , Emily Henderson , Kyoto Prefectural University , Division Of Gastroenterology , Research Center , Niigata University , Graduate School , Dental Sciences , Future Medical Research Center , Designer Cell , E Coli , Hepatocellular Carcinoma ,

New approach could revolutionize the treatment of liver diseases

New approach could revolutionize the treatment of liver diseases
Researchers from Niigata University , the University of Tokyo, Osaka University and Tokyo Medical University, Japan have developed a new approach that could revolutionize the treatment, prevention, and possibly reversal of the damages caused by liver diseases.
This novel strategy exploits small extracellular vesicles (sEVs) derived from interferon-γ (IFN-γ) pre-conditioned MSCs (γ-sEVs).
Cirrhosis and other chronic liver diseases remain a global health concern, with close to 2 million deaths reported annually, these account for approximately 3.5% of annual worldwide deaths.
All these statistics are largely driven by the fact that 75 million of the 2 billion people who consume alcohol worldwide are diagnosed with alcohol-use disorders and are at risk of developing alcohol- induced liver disease. In addition, the high prevalence of viral hepatitis-induced liver damage continues to be on the rise. ....

Atsunori Tsuchiya , Shuji Terai , Suguru Takeuchi , Emily Henderson , Osaka University , Division Of Gastroenterology , University Of Tokyo , Niigata University , Tokyo Medical University , Graduate School , Dental Sciences , Anti Inflammatory , Liver Disease , எமிலி ஹென்டர்சன் , ஒசகக பல்கலைக்கழகம் , பிரிவு ஆஃப் இரைப்பை குடல் , பல்கலைக்கழகம் ஆஃப் டோக்கியோ , நீகாட பல்கலைக்கழகம் , டோக்கியோ மருத்துவ பல்கலைக்கழகம் , பட்டதாரி பள்ளி , டெஂடல் அறிவியல் ,

Study finds new weapon in fight against liver diseases

Study finds new weapon in fight against liver diseases
Study finds new weapon in fight against liver diseases
Last Updated: Sun, May 2nd, 2021, 23:20:09hrs
Tokyo [Japan], May 2 (ANI): During a recent study, researchers developed a new approach that could revolutionise the treatment, prevention, and possibly reversal of the damages caused by liver diseases.
The study by researchers from Niigata University, the University of Tokyo, Osaka University and Tokyo Medical University, Japan was published in the journal npj Regenerative Medicine. This novel strategy exploits small extracellular vesicles (sEVs) derived from interferon-g (IFN-g) pre-conditioned MSCs (g-sEVs).
Cirrhosis and other chronic liver diseases remain a global health concern, with close to 2 million deaths reported annually, these account for approximately 3.5 per cent of annual worldwide deaths. All these statistics are largely driven by the fact that 75 million of the 2 billion people who consume ....

Atsunori Tsuchiya , Shuji Terai , Suguru Takeuchi , Osaka University , Division Of Gastroenterology , University Of Tokyo , Niigata University , Tokyo Medical University , Graduate School , Dental Sciences , ஒசகக பல்கலைக்கழகம் , பிரிவு ஆஃப் இரைப்பை குடல் , பல்கலைக்கழகம் ஆஃப் டோக்கியோ , நீகாட பல்கலைக்கழகம் , டோக்கியோ மருத்துவ பல்கலைக்கழகம் , பட்டதாரி பள்ளி , டெஂடல் அறிவியல் ,

Study finds new weapon in fight against liver diseases

Tokyo [Japan], May 2 (ANI): During a recent study, researchers developed a new approach that could revolutionise the treatment, prevention, and possibly reversal of the damages caused by liver diseases. ....

Atsunori Tsuchiya , Shuji Terai , Suguru Takeuchi , Osaka University , Division Of Gastroenterology , University Of Tokyo , Niigata University , Tokyo Medical University , Graduate School , Dental Sciences , New Weapon , Liver Diseases , Latest Health News , ஒசகக பல்கலைக்கழகம் , பிரிவு ஆஃப் இரைப்பை குடல் , பல்கலைக்கழகம் ஆஃப் டோக்கியோ , நீகாட பல்கலைக்கழகம் , டோக்கியோ மருத்துவ பல்கலைக்கழகம் , பட்டதாரி பள்ளி , டெஂடல் அறிவியல் , புதியது ஆயுதம் ,

A glimmer of hope: New weapon in fight against liver diseases

Niigata University
Niigata, Japan–Researchers from Niigata University , the University of Tokyo, Osaka University and Tokyo Medical University, Japan have developed a new approach that could revolutionize the treatment, prevention, and possibly reversal of the damages caused by liver diseases. This novel strategy exploits small extracellular vesicles (sEVs) derived from interferon-γ (IFN-γ) pre-conditioned MSCs (γ-sEVs).
Cirrhosis and other chronic liver diseases remain a global health concern, with close to 2 million deaths reported annually, these account for approximately 3.5% of annual worldwide deaths. All these statistics are largely driven by the fact that 75 million of the 2 billion people who consume alcohol worldwide are diagnosed with alcohol-use disorders and are at risk of developing alcohol- induced liver disease. In addition, the high prevalence of viral hepatitis-induced liver damage continues to be on the rise. ....

Atsunori Tsuchiya , Shuji Terai , Suguru Takeuchi , Osaka University , Division Of Gastroenterology , University Of Tokyo , Niigata University , Tokyo Medical University , Graduate School , Dental Sciences , ஒசகக பல்கலைக்கழகம் , பிரிவு ஆஃப் இரைப்பை குடல் , பல்கலைக்கழகம் ஆஃப் டோக்கியோ , நீகாட பல்கலைக்கழகம் , டோக்கியோ மருத்துவ பல்கலைக்கழகம் , பட்டதாரி பள்ளி , டெஂடல் அறிவியல் ,