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Photosynthesis of Chiral Building Blocks for Drug Discovery From AsyntMay 19 2021 A new white paper, written by scientists at Liverpool ChiroChem (LCC), describes how the Asynt Illumin8 parallel photoreactor is being used to synthesise a range of new 2-Aryl N-Heterocycles. Liverpool ChiroChem Logo The discovery of a novel enantioselective synthetic pathway for reduction of pyridines to the corresponding chiral piperidines led to the formation of LCC in 2014. Since inception, LCC have enhanced their expertise enabling them to provide leading scientific organisations with access to chirally-pure compounds that play their part in small molecule drug discovery. The white paper describes how using a combination of photoredox-mediated hydrogen atom transfer (HAT) and nickel catalysis - scientists were able to synthesise di- and tri-functionalised

Asynt illuminRoss goodyearShaun smullenLiverpool chirochemFrom asyntmayDrug discoveryமருந்து கண்டுபிடிப்பு