Photosynthesis of Chiral Building Blocks for Drug Discovery
From AsyntMay 19 2021
A new white paper, written by scientists at Liverpool ChiroChem (LCC), describes how the Asynt Illumin8 parallel photoreactor is being used to synthesise a range of new 2-Aryl N-Heterocycles.
Liverpool ChiroChem Logo
The discovery of a novel enantioselective synthetic pathway for reduction of pyridines to the corresponding chiral piperidines led to the formation of LCC in 2014. Since inception, LCC have enhanced their expertise enabling them to provide leading scientific organisations with access to chirally-pure compounds that play their part in small molecule drug discovery.
The white paper describes how using a combination of photoredox-mediated hydrogen atom transfer (HAT) and nickel catalysis - scientists were able to synthesise di- and tri-functionalised
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Colloidal Nanoparticles Advance Frontiers of Synthetic Chemistry
From AsyntMay 5 2021
Researchers from the School of Chemistry at the University of St Andrews (UK) are using a DrySyn Spiral Evaporator from Asynt to help synthesize novel reactive colloidal nanoparticles that present an exciting tool to create a new generation of smart nanomaterials.
Virginie Viseur from the Kay Group operating the DrySyn Spiral Evaporator
The unique properties of nanomaterials mean that potential applications extend from use in smart drug delivery systems through to new catalysts and helping to deliver greater efficiency in solar cells. However, the field is still restricted by limited synthetic capabilities.