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SARPAC Clinical Trial of Leukine® (sargramostim, rhu GM-CSF) in Hospitalized COVID-19 Patients Meets Primary Endpoint of Significant Improvement in Lung Function


COVID-19) study of inhaled Leukine
® (sargramostim, yeast-derived recombinant human GM-CSF) in hospitalized COVID-19 patients (NCT04326920).
1,2 This prospective, randomized, open-label study was led by University Hospital Ghent and conducted at five hospitals in Belgium. The study enrolled 81 patients with PCR-confirmed COVID-19 who were suffering from acute hypoxic respiratory failure requiring supplemental oxygen. The full study and translational results are being prepared for publication.
Lung dysfunction resulting in hypoxemia has been a hallmark of severe cases of COVID-19.
3,4,5  SARPAC was launched based on GM-CSF s role in restoring alveolar macrophages that have anti-inflammatory properties and serve to remove pathogens and other debris while maintaining alveolar surfactant. ....

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Why sleep apnea can set you up for a severe COVID-19 infection


Why sleep apnea can set you up for a severe COVID-19 infection
About 18 million Americans, or one in every 15 people, live with a sleep disorder that is not only inconvenient but can be life-threatening.
Sleep apnea is a disorder that affects breathing during sleep (‘apnea’ comes from a Greek word meaning “want of breath”).
Sleep apnea is not only a chronic condition, but it also is progressive, meaning it can get worse over time.
The most common form of sleep apnea is obstructive sleep apnea (OSA), where the soft tissue in the back of the throat collapses during sleep, blocking the flow of air. ....

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