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Singapore scientists uncover a crucial link between cholesterol synthesis and cancer progression

Singapore scientists uncover a crucial link between cholesterol synthesis and cancer progression
asiaresearchnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from asiaresearchnews.com Daily Mail and Mail on Sunday newspapers.

David Virshup , Dean For Research At , Clinical Investigation , Assistant Professor Babita Madan , Stem Cell Biology , Singapore Wnt , Professor David Virshup , Professor Patrick Tan , Senior Vice Dean ,

Singapore scientists uncover a crucial link b

<p>A study led by Duke-NUS Medical School has found an important connection between cancer, stem cells and the building blocks of cholesterol. Specifically, the research reveals how the enzyme FAXDC2 influences cancer cell growth and differentiation through its role in cholesterol synthesis, suggesting possible new approaches to cancer treatment.</p>
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David Virshup , Dean For Research At , Method Of Research , Clinical Investigation , Assistant Professor Babita Madan , Stem Cell Biology , Singapore Wnt , Professor David Virshup , Professor Patrick Tan , Senior Vice Dean ,

Scientists uncover a crucial link between cholesterol synthesis and cancer progression

Scientists uncover a crucial link between cholesterol synthesis and cancer progression
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

David Virshup , Babita Madan , Clinical Investigation , Assistant Professor Babita Madan , Stem Cell Biology , Singapore Wnt , Professor David Virshup ,

Study could lead to the development of novel treatments for drug-resistant cancers

Study could lead to the development of novel treatments for drug-resistant cancers
ETC-159, a made-in-Singapore anti-cancer drug that is currently in early phase clinical trials for use in a subset of colorectal and gynecological cancers, could also prevent some tumors from resisting therapies by blocking a key DNA repair mechanism, researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research (A STAR) in Singapore reported in the journal
EMBO Molecular Medicine.
Among the many therapies used to treat cancers, inhibitors of the enzyme poly (ADP ribose) polymerase (PARP) prevent cancer cells from repairing naturally occurring DNA damage, including unwanted/harmful breaks in the DNA. When too many breaks accumulate, the cell dies. ....

Ann Lee , David Virshup , Emily Henderson , Agency For Science , Experimental Drug Development Centre , Assistant Professor Babita Madan , Stem Cell Biology , Professor David Virshup , Dna Damage , Medical School , Stem Cells , Wnt Signalling , ஆண்டு லீ , எமிலி ஹென்டர்சன் , சோதனை மருந்து வளர்ச்சி மையம் , உதவியாளர் ப்ரொஃபெஸர் பாபிடா மதன் , தண்டு செல் உயிரியல் , டீயெநே சேதம் , மருத்துவ பள்ளி , தண்டு செல்கள் ,

Double trouble for drug-resistant cancers

New research from Duke-NUS Medical School, and the Agency for Science, Technology and Research identifies chemotherapy-resistant cancers escape mechanism, which offers new anti-cancer treatment options. ....

Ann Lee , David Virshup , Agency For Science , Experimental Drug Development Centre , Assistant Professor Babita Madan , Stem Cell Biology , Professor David Virshup , Cell Biology , Medicine Health , Clinical Trials , ஆண்டு லீ , சோதனை மருந்து வளர்ச்சி மையம் , உதவியாளர் ப்ரொஃபெஸர் பாபிடா மதன் , தண்டு செல் உயிரியல் , செல் உயிரியல் , மருந்து ஆரோக்கியம் , மருத்துவ சோதனைகள் ,