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EULAR SSc Recommendations Now Include Immunosuppressants

The update to 2017 recommendations include targeted synthetic and biologic disease-modifying antirheumatic drugs for the first time. ....

Ariane Herrick , European Alliance Of Associations , European Congress , University Of Manchester England , Boehringer Ingelheim , European Alliance , Del Galdo , Leeds Teaching Hospital , Scleroderma Trials , Crest Syndrome , Biologic Therapy , Pulmonary Hypertension , Systemic Sclerosis , Diffuse Scleroderma , Interstitial Lung Disease , Heart Failure , Lung Fibrosis , Pulmonary Fibrosis , Ibrosis Pulmonary , Monoclonal Antibody , Antineoplastic Drug , Nti Cancer Agents ,

Vicore Pharma's drug candidate C21 dilates peripheral resistance vessels in fibrotic disease

Vicore Pharma s drug candidate C21 dilates peripheral resistance vessels in fibrotic disease
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GOTHENBURG, Sweden, March 11, 2021 /PRNewswire/
Vicore Pharma Holding AB (publ), a pharmaceutical company developing innovative medicines for severe lung disorders such as idiopathic pulmonary fibrosis (IPF), today announces top line data from a phase II study of its oral angiotensin II type 2 receptor (AT2R) agonist C21 in patients with systemic sclerosis and Raynaud s phenomenon. In this mechanistic 12-person single-dose study, C21 did not reach the predefined area-under-curve endpoint but at the end of the measurement C21 treatment showed statistically significant evidence of restored skin temperature as a measure of dilated peripheral resistance vessels. ....

Vastra Gotalands Lan , Vicore Pharma , Ariane Herrick , Carl Johan Dalsgaard , Prnewswire Vicore Pharma Holding , University Of Manchester , Vicore Pharma Holding , Professor Ariane Herrick , Salford Royal Hospital , Johan Dalsgaard , Pharma Holding , Vicore Pharma Holding Ab , அரியேன் ஹெரிக் , பல்கலைக்கழகம் ஆஃப் மான்செஸ்டர் , ப்ரொஃபெஸர் அரியேன் ஹெரிக் , சால்ஃபோர்ட் அரச மருத்துவமனை , பார்மா வைத்திருத்தல் ,