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New molecule targets key protein in autoimmune diseases

Scientists from Scripps Research have developed a small molecule that blocks the activity of a protein linked to autoimmune diseases, including systemic lupus erythematosus (SLE) and Crohn's disease. ....

Bruce Beutler , John Teijaro , Christopher Parker , University Of Texas Southwestern Medical Center , Genetics At Scripps Research , Scripps Research , Department Of Immunology , Department Of Chemistry At Scripps Research , Scripps Research Institute , Nature Chemical Biologyon January , Texas Southwestern Medical Center , Ari Theofilopoulos , Crohn 39s Disease , Lupus Erythematosus , Small Molecules , Systemic Lupus Erythematosus ,

New immune system-targeting compounds shows e

<p>Scripps Research scientists developed a compound that can block a protein previously considered challenging to drug and is implicated in autoimmune diseases, including lupus.</p>
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Weichao Li , Argyriosn Theofilopoulos , Daniel Lazar , Appasom Jadhav , John Teijaro , Christopher Parker , Appaso Jadhav , Nathalia Gazaniga , Wesleyw Wang , Jacobm Wozniak , Bruce Beutler , Chiu Danielc Lazar , Skaggs Graduate School , University Of Texas Southwestern Medical Center , Scripps Research , National Institute Of Allergic , Department Of Immunology , Scripps Research Translational Institute , Genetics At Scripps Research , Department Of Chemistry At Scripps Research , Nature Chemical Biologyon January , Texas Southwestern Medical Center , Ari Theofilopoulos , Tzu Yuan Chiu Daniel , National Institute , Infectious Diseases ,

New immune system-targeting compound shows early promise in treating lupus

New immune system-targeting compound shows early promise in treating lupus
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Christopher Parker , Jacobm Wozniak , Weichao Li , Nathalia Gazaniga , John Teijaro , Bruce Beutler , Wesleyw Wang , Chiu Danielc Lazar , Appasom Jadhav , Argyriosn Theofilopoulos , Department Of Chemistry At Scripps Research , Scripps Research , Genetics At Scripps Research , University Of Texas Southwestern Medical Center , Department Of Immunology , Nature Chemical Biology , Texas Southwestern Medical Center , Ari Theofilopoulos , Tzu Yuan Chiu Daniel , Tzu Yuan Chiu , Nature Chemical ,