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Background Currently, disease control in patients with severe eosinophilic asthma is not optimistic. Competing endogenous RNA (ceRNA) networks have been found to play a key role in asthma in recent years. However, it is unclear whether ceRNA networks play an important part in severe eosinophilic asthma. Methods Firstly, gene expression profiles related to severe eosinophilic asthma were downloaded from the Gene Expression Omnibus (GEO) database. Secondly, the key modules were identified by the weighted gene co-expression network analysis (WGCNA). Thirdly, genes in modules highly associated with severe eosinophilic asthma were selected for further construction of the ceRNA network. Fourthly, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed on hub genes. Finally, the results of this study were validated on the GSE143303, GSE137268, and GSE147878 datasets. Results 22 severe eosinophilic asthmatics and 13 healthy controls were extract ....
Cardioprotective Role of Myeloid-Derived Suppressor Cells in Heart Failure ahajournals.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from ahajournals.org Daily Mail and Mail on Sunday newspapers.
OPINIÃO DO LEITOR - O que se leva da vida folhadelondrina.com.br - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from folhadelondrina.com.br Daily Mail and Mail on Sunday newspapers.