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Research: Varied COVID-19 Risk Among Immunocompromised Patients

Research: Varied COVID-19 Risk Among Immunocompromised Patients
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United States , Markj Siedner , Shruti Sagar , Yijia Li , Rebeccaf Gilbert , Matthewa Getz , Rockib Uddin , Manuela Cernadas , Manishc Choudhary , Jonathan Li , Jamesp Flynn , Bina Choi , Rinki Deo , James Regan , Mamadou Barry , Yee Liew , Zacharys Wallace , Gregorye Edelstein , Gauravd Gaiha , Dessie Tien , Yumeko Kawano , Lewisa Novack , Tessa Speidel , Zahra Reynold , Amyk Barczak , Jacobe Lemieux ,

Covid infection, vax boosts T cell immune responses against Omicron

T cell responses are still robust against the variant in most individuals with prior SARS-CoV-2 infection or vaccination, despite low antibody responses, finds a study.This also provides protection against severe disease, said researchers at . ....

New York , United States , Dana Farber Cancer Institute , Anusha Nathan , Vivek Naranbhai , Gauravd Gaiha , Ragon Institute , Massachusetts General Hospital , Dana Farber Cancer ,

Alternative COVID-19 Vaccine That Uses T-Cells Will Likely Target Mutant Variants

Alternative COVID-19 Vaccine That Uses T-Cells Will Likely Target Mutant Variants
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Anusha Nathan , Gaurav Gaiha , Elizabeth Rossin , Altered Spike Protein , Beta Variants Challenges Immunity , Improved Vaccine ,

Structure-guided T cell vaccine design could offer broad protection SARS-CoV-2 variants


Structure-guided T cell vaccine design could offer broad protection SARS-CoV-2 variants
Gaurav Gaiha, MD, DPhil, a member of the Ragon Institute of MGH, MIT and Harvard, studies HIV, one of the fastest-mutating viruses known to humankind. But HIV s ability to mutate isn t unique among RNA viruses most viruses develop mutations, or changes in their genetic code, over time. If a virus is disease-causing, the right mutation can allow the virus to escape the immune response by changing the viral pieces the immune system uses to recognize the virus as a threat, pieces scientists call epitopes.
To combat HIV s high rate of mutation, Gaiha and Elizabeth Rossin, MD, PhD, a Retina Fellow at Massachusetts Eye and Ear, a member of Mass General Brigham, developed an approach known as structure-based network analysis. With this, they can identify viral pieces that are constrained, or restricted, from mutation. Changes in mutationally constrained epitopes are rare, as they can cause t ....

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