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Concomitant selective serotonin reuptake inhibitors and oral anticoagulants may increase risk of bleeding

1. This case-control study found that in patients with atrial fibrillation concomitant Serotonin Reuptake Inhibitor (SSRI) and Oral Anticoagulants (OAC) was associated with an increased risk of major bleeding compared with OAC use alone. 2. This increased risk was highest in the first 30 days of continuous, concomitant use. Evidence Rating Level: 2 (Good) Antidepressants, ....

United Kingdom Clinical Practice Research Datalink , Serotonin Reuptake Inhibitor , Oral Anticoagulants , Rating Level , Atrial Fibrillation ,

Use of direct oral anticoagulants should not delay surgical intervention for patients with hip fractures

1. In geriatric patients with hip fractures on direct oral anticoagulants (DOACs), surgical treatment within 48 hours of their last preoperative DOAC dose had comparable complication rates and 1-year mortality compared with patients with surgery delayed past 48 hours. 2. Patients who underwent surgical management within 48 hours required fewer transfusions and had decreased length ....

United States , Rating Level , Charlson Comorbidity Index , Emergency Medicine , Hip Fracture , Orthopedic Surgery ,

#VisualAbstract: Apixaban does not significantly prevent recurrent stroke after cryptogenic stroke in patients with atrial cardiopathy

Click here to read this study in JAMA. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc. ....

Minute Medicine Inc , Antiplatelet Therapy , Atrial Cardiopathy , Cryptogenic Stroke , Recurrent Stroke , Stroke Prevention ,

New Data on Antithrombotics in Cervical Artery Dissection

The STOP-CAD study signaled a short course of an antithrombotic regimen might lower ischemic stroke risk in some patients without significantly increasing major bleeding. ....

Brown University , Rhode Island , United States , University Of Kentucky , Larryb Goldstein , Shadi Yaghi , Clinical Research , International Stroke Conference , Department Of Neurology , American Heart Association , Medscape Medical , Medscape Medical News , Scientific Statement , Stroke Cerebrovascular Accident Cva , Anticoagulation Therapy , Ischemic Stroke Ischaemic , Anti Thrombotics , Antithrombotic Therapy , Antithrombotic Agents , Intracranial Hemorrhage , Ntracranial Bleeding Intracranial Haemorrhage , Stroke Risk , Practice Management ,

What's the Best Antithrombotic Therapy Post TMVR?

New observational data suggested direct oral anticoagulants may be the optimal antithrombotic regime after transcatheter mitral valve replacement; randomized trials were needed. ....

France General , Nathan El , Department Of Cardiology , Journal Of The American College Cardiology , Cardiovascular Research Institute , Maastricht University Center , Paris City University , Antonius Hospital , American College , Cardiac Surgeries , Cardiac Surgery , Anti Thrombotics , Antithrombotic Therapy , Antithrombotic Agents , Anticoagulation Therapy , Cardiovascular Imaging , Ardiac Imaging , V Imaging , Stroke Cerebrovascular Accident Cva , Computed Tomography , Ct Scan , Mitral Valve , Valve Replacement ,