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Key Takeaways From ANNEXA-I Study

Dr Connolly highlights the cautious patient selection and the significance of reducing hematoma expansion for improved outcomes in cases of intracerebral hemorrhage (ICH) associated with the use of a reversal agent for factor Xa inhibitors. ....

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ANNEXA-I Study Overview

A medical expert discusses the findings of a randomized trial investigating the use of andexanet alfa versus usual care in patients with acute intracerebral hemorrhage (ICH) and recent direct oral anticoagulant (DOAC) use. ....

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ANNEXA-I: Andexanet Alfa Shows Efficacy, Safety for Factor Xa Reversal in Acute ICH

The phase 4 ANNEXA-I trial was stopped early after showing superior hemostatic efficacy and the capability to limit potentially life-threatening intracerebral hemorrhage (ICH) compared with usual care in patients taking oral factor Xa (FXa) inhibitors. ....

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Andexxa Phase IV trial stopped early after achieving pre-specified criteria on haemostatic efficacy versus usual care

AstraZeneca to proceed with regulatory filings to convert from conditional to full approval in the US and EU
ANNEXA-I, a post-marketing Phase IV trial to assess the efficacy and safety of Andexxa in. | June 5, 2023 ....

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ANDEXXA Phase IV Trial Stopped Early After Achieving Pre-specified Criteria on Hemostatic Efficacy Versus Usual Care

AstraZeneca to proceed with regulatory filings to convert from conditional to full approval in the US and EU

. | June 5, 2023 ....

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