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Stuart J. Connolly, Clinical Trialist and Arrhythmia Medicine Pioneer, Dies at 75

Stuart J. Connolly, Clinical Trialist and Arrhythmia Medicine Pioneer, Dies at 75
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Jeff-healey

Andexanet yields better control of hematoma expansion than usual care, finds study

For patients who had taken factor Xa inhibitors within 15 hours before having an acute intracerebral hemorrhage, andexanet alfa, which reverses the effects of factor Xa inhibitors, results in better control of hematoma expansion than usual care, according to a study published in the New England Journal of Medicine.

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Mcmaster-university
New-england-journal
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Intracerebral-hemorrhage

Key Takeaways From ANNEXA-I Study

Dr Connolly highlights the cautious patient selection and the significance of reducing hematoma expansion for improved outcomes in cases of intracerebral hemorrhage (ICH) associated with the use of a reversal agent for factor Xa inhibitors.

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Intracerebral-hemorrhage
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Direct-oral-anticoagulant
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Top in cardiology: Iron injection for heart failure; ANNEXA phase IV trial stopped

The FDA has approved the first-ever IV iron replacement therapy to improve exercise capacity in adults with heart failure. The IV ferric carboxymaltose injection (Injectafer; Daiichi Sankyo Inc./American Regent) was approved for patients with New York Heart Association class II/III heart failure, which is defined as a slight or marked limitation of physical activity due to fatigue, palpitation

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Healio-coverage

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