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Since the advent of Tissue Engineering (TE) in the late 1980’s, significant progress has been made within the biomedical landscape. A recently established branch within TE is biofabrication, a field that aims to automate the fabrication of biologically functional materials through the use of additive manufacturing or three-dimensional (3D) printing, among other techniques. Additive manufacturing offers fine control over part porosity, with the capacity to match the complex internal architecture of human bone. Coupled with clinical 3D scanning techniques, 3D printing has the capacity to generate implants that accurately match defected areas. However, due to the limited number of regulatory approved devices for human implantation and high cost of sophisticated powder bed fusion printers, the printing techniques are restricted. To be compatible with regulatory requirements, this work aims to utilise a widely accessible and regulatory approved device, high-density polyethylene (HDPE) to

United statesTherapeutic goods administrationAnatomics pty ltdDrug administrationTissue engineeringFederal drug administration3d printingTissue engineering