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New drug candidate reverses obesity in mice by transforming liver metabolism

A mitochondrial transcription inhibitor (IMT) shifted metabolism in high-fat diet mice toward fatty acid oxidation, leading to weight loss, reduced liver fat, and improved glucose tolerance. ....

Lab Animal Monitoring System , Nature Metabolism , Comprehensive Lab Animal Monitoring System , Taolin Yuan , Postdoctoral Researcher , Professor Nils G , Principal Investigator , Weight Loss ,

Nutrition's crucial role in Alzheimer's progression revealed

Study highlights the strong association between nutrition, particularly malnutrition, and the risk and progression of Alzheimer's disease, emphasizing early dietary interventions as key to reducing AD's global burden. ....

Adisak Riwkratok , Capital Medical University , European Society For Clinical Nutrition , Global Leadership Initiative On Malnutrition , Department Of Neurology , European Society , Clinical Nutrition , Cognitive Neurology , Beijing Tiantan Hospital , Capital Medical , Global Leadership Initiative , Lzheimer 39s Disease ,

Enrichment and sequencing of albumin protein from urine

The importance of identifying and analyzing protein markers in biofluids, particularly in urine for disease monitoring. ....

Application Note ,

Innovative COVID-19 test prototype uses bioluminescence for speedier results

Researchers used a luciferase-independent luminescence test to investigate whether the wild-type SARS-CoV-2 spike protein possesses pseudo-luciferase activity for Cypridina luciferin. ....

Myriamb Shutterstock , Autodock Vina , Pseudo Luciferase Activity , Image Credit , Coronavirus Disease Covid 19 , Covid 19 , Polymerase Chain Reaction , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein ,

Combination therapy of dapagliflozin and semaglutide shows superior efficacy in type 2 diabetes management

Study demonstrates that combining dapagliflozin and semaglutide significantly improves glycemic control and other health parameters in type 2 diabetes patients, outperforming dapagliflozin alone. ....

Dragana Gordic , Pharmacological Research , International Diabetes Federation , Diabetes Atlas , Kidney Disease Improving Global Outcomes , Type 2 Diabetes , Blood Pressure , Body Mass Index , Diabetes Mellitus , Glycated Hemoglobin ,