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New drug candidate reverses obesity in mice by transforming liver metabolism

A mitochondrial transcription inhibitor (IMT) shifted metabolism in high-fat diet mice toward fatty acid oxidation, leading to weight loss, reduced liver fat, and improved glucose tolerance. ....

Lab Animal Monitoring System , Nature Metabolism , Comprehensive Lab Animal Monitoring System , Taolin Yuan , Postdoctoral Researcher , Professor Nils G , Principal Investigator , Weight Loss ,

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' powerhouses, the mitochondria. ....

Karolinska Institutet , Novo Nordisk Foundation , Swedish Brain Foundation , Pretzel Therapeutics Inc , Swedish Diabetes Foundation , Swedish Cancer Society , Discovery Center , Swedish Research Council , Alice Wallenberg Foundation , Department Of Medical Biochemistry , Nature Metabolism , Medical Biochemistry , Professor Nils G , Swedish Brain , Pretzel Therapeutics , Lead Discovery Center , Fatty Liver ,

New drug candidate reverses obesity in mice

New drug candidate reverses obesity in mice
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Karolinska Institutet , Department Of Medical Biochemistry , Nature Metabolism , Taolin Yuan , Medical Biochemistry , Professor Nils G ,

Three KI Researchers Awarded Prestigious ERC Grant

Three KI Researchers Awarded Prestigious ERC Grant
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Johannes Frands , Karolinska Institutet , Leona Rohrbeck , Juleen Zierath , El Manira , Abdel El Manira , Lasse Skog , Department Of Neuroscience , Department Of Molecular Medicine , University Of Copenhagen , Department Of Physiology , European Research Council , Department Of Medical Biochemistry , Professor Nils G , Professor Juleen Zierath , Medical Biochemistry , Professor Larsson , Professor El Manira , Molecular Medicine , Professor Zierath , European Research ,

New study questions the role of supercomplexes in metabolism and disease

New study questions the role of supercomplexes in metabolism and disease
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Dusanka Milenkovic , Karolinska Institutet , Molecular Metabolism Division , Department Of Medical Biochemistry , Cell Metabolism , Professor Nils G , Medical Biochemistry ,