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Abatacept, cenicriviroc, or infliximab does not decrease time to recovery for hospitalized patients with COVID-19 pneumonia

1. There was no statistically significant difference in recovery time in patients with COVID-19 pneumonia using treatment with abatacept, cenicriviroc, or infliximab compared to standard care. 2. Safety assessment endpoints showed no significant difference between the trial drugs and placebo, as both groups had a similar incidence of serious adverse events (SAE). Evidence Rating Level:

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis. William G. Powderly, MD, (right) who led the large clinical trial, discusses patient conditions with Maanasi Samant, MD, in the intensive care unit at Barnes-Jewish Hospital, one of the major trial sites, during the COVID-19 pandemic.

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