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Mustang Bio & City of Hope: CAR-T Cell Therapy Extends Treatment Refractory Glioblastoma Survival

Half the individuals receiving the new CAR-T cell therapy achieved stable disease or better. Intratumoral, intraventricular, and intratumoral + intraventricular administration routes all were generally well tolerated. The Latest A recent phase 1 clinical trial by Brown et al. and funded by Mustang Bio and City of Hope investigated CAR-T cell therapy for the ....

United States , Minute Medicine Inc , American Association Of Neurological Surgeons , Company History , Mustang Bio , American Association , Neurological Surgeons , Chimeric Antigen Receptor , Non Hodgkins Lymphoma , Chronic Lymphocytic Leukemia , Runway Growth , City Of Hope , Clinical Trial , 2 Minute Medicine ,

Wellness Check: Sleep | 2 Minute Medicine

Cognitive-behavioural therapy improves sleep in patients with mild cognitive impairment 1. In patients with mild cognitive impairment, empowerment-based cognitive behavioural therapy was shown to improve sleep and cognition after 6 months. 2. Patients receiving cognitive behavioural therapy had a greater reduction in insomnia and greater improvement in global cognition when compared to patients receiving standard ....

Hong Kong , Minute Medicine Inc , Rating Level , Pittsburg Sleep Quality Index , Insomnia Severity Index , Machine Learning , Shift Work , 2 Minute Medicine ,

At-Home Eccentric Exercises Improve Functional Ability More Than Stretching in Older Women

1. At-home eccentric exercise produced more improvement in muscular peak torque and gait speed than static stretching or dynamic closed-chain stretching. 2. At-home eccentric exercise, static stretching, and dynamic closed-chain stretching all improved hamstring flexibility and passive ankle dorsiflexion. Evidence Rating Level: 1b A large detriment of aging is the reduction of functional ability. A ....

Minute Medicine Inc , Rating Level , Physical Activity Readiness Questionnaire , Dynamic Stretching , Gait Speed , Static Stretching , 2 Minute Medicine ,

Sleep duration may be linked to periodontitis and tooth loss in adults

1. In this cross-sectional study, there was a significant association between insufficient sleep duration and the presence of moderate or severe periodontitis and tooth loss. 2. Furthermore, both insufficient and excessive sleep were associated with increasing periodontitis. Evidence Rating Level: 3 (Average) Periodontitis is a highly prevalent condition and is the main cause of tooth ....

United States , American Periodontal Association , National Health , Rating Level , Nutrition Examination Surveys , Tooth Loss , 2 Minute Medicine , Infectious Disease ,

High-Dose Docosahexaenoic Acid Does Not Improve Behavioral Functioning in Preterm Infants at 5 Years of Age

1. Docosahexaenoic acid supplementation at the in utero dose for infants born at less than 29 weeks gestation did not improve behavioral and emotional functioning at 5 years of age. 2. No differences in executive functioning or health were found between the children who had received high-dose docosahexaenoic acid and the children who had not. ....

Rating Level , Difficulties Questionnaire , Pediatric Quality , Life Inventory , Public Health , 2 Minute Medicine , Chronic Disease ,