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Differing immune reponses discovered in asymptomatic cases versus those with severe COVID-19 – Wellcome Sanger Institute

News Article by the Communications Team
20 Apr 2021
Using data from the Human Cell Atlas, researchers have identified the differences in immune cells’ response in those who had no symptoms compared to severe symptoms.
The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.
Researchers from the Wellcome Sanger Institute, Newcastle University, University College London, University of Cambridge, EMBL’s European Bioinformatics Institute (EMBL-EBI) and their collaborators within the Human Cell Atlas initiative, found raised levels of specific immune cells in asymptomatic people. They also showed people with more serious symptoms had lost these protective cell types, but gained inflammatory cells. These differences in the immune response could help explain serious lung inflammation and blood ....

United Kingdom , City Of , Kelvin Zewen Tuong , Menna Clatworthy , Sarah Teichmann , John Marioni , Emuzlifah Haniffa , University College London , Cancer Research United Kingdom Cambridge Institute , Head Of Research , Human Cell Atlas Organising Committee , Wellcome Sanger Institute , Senior Group Leader , Wellcome Sanger Institute Associate Faculty , Newcastle University , University Of Cambridge , European Bioinformatics Institute , Clatworthy Lab , Human Cell Atlas , Bioinformatics Institute , Nature Medicine , Human Cell , Senior Clinical Fellow , Wellcome Sanger , Translational Immunology , Wellcome Sanger Institute Associate ,

Cytosponge-AI combo could help doctors diagnose Barretts oesophagus

Cytosponge-AI combo could help doctors diagnose Barretts oesophagus
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United Kingdom , Marcel Gehrung , Michelle Mitchell , Cancer Research United , University Of Cambridge , Cancer Research United Kingdom Cambridge Institute , Cancer Research United Kingdom , Cancer Research United Kingdom Funded , Nature Medicine , ஒன்றுபட்டது கிஂக்டம் , மைக்கேல் மிட்செல் , புற்றுநோய் ஆராய்ச்சி ஒன்றுபட்டது , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , புற்றுநோய் ஆராய்ச்சி ஒன்றுபட்டது கிஂக்டம் கேம்பிரிட்ஜ் நிறுவனம் , புற்றுநோய் ஆராய்ச்சி ஒன்றுபட்டது கிஂக்டம் , புற்றுநோய் ஆராய்ச்சி ஒன்றுபட்டது கிஂக்டம் நிதியுதவி , இயற்கை மருந்து ,

Inivata Presents New Data in Support of its Liquid Biopsy Technologies at AACR Virtual Annual Meeting 2021

Inivata Presents New Data in Support of its Liquid Biopsy Technologies at AACR Virtual Annual Meeting 2021
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The ISSCR launches new digital scientific series on computational stem cell biology

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The International Society for Stem Cell Research (ISSCR) is launching a new three-part digital series on Computational Stem Cell Biology starting 15 March, 2021. This series is part of the Society s growing portfolio of topic-specific digital scientific programming for members - also offered to non-members for fee. All ISSCR Digital programs are available live and on-demand.
This series explores the groundbreaking advances in RNA- and DNA-sequencing and bioinformatic technologies that have presented stem cell biologists with new insights into complex biological, developmental, and disease processes. This programming focuses on the latest developments in this rapidly advancing field.
Part 1: Exploring Stem Cells with Single Cell and Combinatorial Analyses ....

South Australia , United States , United Kingdom , Sara Jane Dunn , Patrick Cahan , Peter Zandstra , Barbara Treutlein , Owen Rackham , Jay Shin , Josem Polo , Shila Ghazanfar , Sarah Pierce , Samantha Morris , Kym Kilbourne , Himanshu Kaul , Johns Hopkins University , Cancer Research United Kingdom Cambridge Institute , Monash University , International Society For Stem Cell Research , Genome Institute Of Singapore , Integrative Medical Sciences , University Of British Columbia , University Of Melbourne , Murdoch Children Research Institute , Stanford University , Washington University In St ,

Changes can be detected in BRCA1 breast cells before they turn cancerous

Changes can be detected in BRCA1 breast cells before they turn cancerous
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United Kingdom , Karsten Bach , Sara Pensa , Michelle Mitchell , University Of Cambridge , Cancer Research United Kingdom Cambridge Institute , Nature Communications , Senior Research , Stem Cell Institute , Cancer Research United Kingdom , Department Of Pharmacology , Senior Research Associate , Cell Institute , ஒன்றுபட்டது கிஂக்டம் , மைக்கேல் மிட்செல் , பல்கலைக்கழகம் ஆஃப் கேம்பிரிட்ஜ் , புற்றுநோய் ஆராய்ச்சி ஒன்றுபட்டது கிஂக்டம் கேம்பிரிட்ஜ் நிறுவனம் , இயற்கை தகவல்தொடர்புகள் , மூத்தவர் ஆராய்ச்சி , தண்டு செல் நிறுவனம் , புற்றுநோய் ஆராய்ச்சி ஒன்றுபட்டது கிஂக்டம் , துறை ஆஃப் மருந்தியல் , மூத்தவர் ஆராய்ச்சி இணை , செல் நிறுவனம் ,