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Welcome To IANS Live - SCIENCE - Record group meet transcriptions with new Microsoft app

A product of Microsoft s experimental division Garage, Group Transcribe uses a multi-device approach to provide real-time, high quality transcription and translation, so users can be more present and productive during in-person meetings and conversations.

New delhiIndia privateNews serviceGroup transcribeAll rightsபுதியது டெல்ஹிஇந்தியா ப்ரைவேட்செய்தி சேவைஅனைத்தும் உரிமைகள்

CRISPR screen identifies clinically approved immunosuppressants that could treat coronavirus infections

CRISPR screen identifies clinically approved immunosuppressants that could treat coronavirus infections Researchers in Switzerland and Germany have identified host cell factors required for coronavirus replication that could serve as targets for treatment with clinically-approved drugs. The team found that several autophagy-related genes were common host defense factors required for the replication of both endemic and emerging coronaviruses. These coronaviruses include the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic. Autophagy – cellular response to stressors such as hypoxia or infection – involves the recycling of proteins and organelles to maintain homeostasis. Various trafficking pathways enable the transportation of cytoplasmic material to the lysosome, where it is destroyed.

Nordrhein westfalenVolker thielMeletios verras shutterstockSally robertsonInstitute of virologyMeletios verrasMiddle easternCorona virusCoronavirus disease covid 19Mers covSars cov 2Severe acute respiratorySevere acute respiratory syndromeனோற்ர்ேன் வெஸ்ட்ஃபாலன்வோல்கர் திீஏல்சாலி ராபர்ட்சன்

High-throughput genetic analysis can help dissect the mechanism of disease inheritance

High-throughput genetic analysis can help dissect the mechanism of disease inheritance Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited. An international research team, including a biomedical scientist from City University of Hong Kong (CityU), has developed a high-throughput biological assay technique which enabled them to conduct a systematic analysis on the impact of nearly 100,000 genetic variants on the binding of transcription factors to DNA. Their findings provided valuable data for finding key biomarkers of type 2 diabetes for diagnostics and treatments. And they believe that the new technique can be applied to studies of variants associated with other genetic diseases.

United kingdomBing renJussi taipaleEmily hendersonYan jianUniversity of cambridgeUniversity of california san diegoDepartment of biomedical sciences at cityCity university of hong kongCity universityHong kongAssistant professorBiomedical sciencesProfessor bing renCalifornia san diegoProfessor jussi taipale

Kronos Bio Announces First Patient Dosed in Phase 1/2 Clinical Trial of KB-0742, an Oral CDK9 Inhibitor Targeting MYC-amplified Cancers

Kronos Bio Announces First Patient Dosed in Phase 1/2 Clinical Trial of KB-0742, an Oral CDK9 Inhibitor Targeting MYC-amplified Cancers
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Kronos bioTranscription factorClinical developmentClinical trialSolid tumorsகுரோனோஸ் உயிர்படியெடுத்தல் காரணிமருத்துவ வளர்ச்சிமருத்துவ சோதனை

No evidence of SARS-CoV-2 fusing into the human genome

New data from researchers led by Majid Kazemian from Purdue University refutes claims from recent studies suggesting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could create a host-virus chimeric RNA. Their team found SARS-CoV-2 does not combine with the human genome.

Jocelyn solis moreirafebMajid kazemianJocelyn solis moreiraPurdue universitySars cov 2Corona virusCoronavirus disease covid 19In vitroIrna sequencingSevere acute respiratorySevere acute respiratory syndromeஜாஸ்லைந் ஸோலிஸ் மோர்ரபர்‌ட்யூ பல்கலைக்கழகம்கொரோனா வைரஸ்இல் விட்ரோர்ந வரிசைப்படுத்துதல்