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Bristol Myers pays Agenus $200M for drug aimed at top immunotherapy target


Dive Brief:
Bristol Myers Squibb on Tuesday said it will pay $200 million to acquire rights to an experimental cancer immmunotherapy developed by Massachusetts biotech Agenus.
Per deal terms, Bristol Myers could pay Agenus up to $1.36 billion more in conditional payments if certain development, regulatory and marketing milestones are hit. Agenus also retains certain options to participate in testing the drug or, if it s ever approved by the Food and Drug Administration, co-promote it in the U.S. 
The drug, which could enter clinical testing later this year, is aimed at a protein target called TIGIT that s lately become of interest to several top cancer drugmakers, including Merck & Co., Roche and Gilead.  ....

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Arcus Biosciences Reports First Quarter 2021 Financial Results and Provides Operational Highlights


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Arcus Biosciences Reports First Quarter 2021 Financial Results and Provides Operational Highlights
Continued to advance our portfolio of anti-TIGIT antibodies: On track for the ARC-7 interim analysis for domvanalimab in 2Q21, and the first patient was dosed with AB308 in combination with zimberelimab
Presented promising PFS and OS data for etrumadenant in the ≥3L metastatic colorectal cancer setting at AACR
Initiated the randomized portion of our ARC-8 study evaluating AB680, our first-in-class small molecule CD73 inhibitor, in pancreatic cancer following rapid completion of enrollment of the dose-expansion portion of the study
Presented preclinical data on a novel series of HIF-2α ....

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Ligand Pharmaceuticals Inc (LGND) Q1 2021 Earnings Call Transcript


Ligand Pharmaceuticals Inc (LGND) Q1 2021 Earnings Call Transcript
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Ligand Pharmaceuticals Inc (NASDAQ: LGND)
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Operator
Good afternoon, and thank you for standing by. Welcome to the Ligand Pharmaceuticals Quarter One Earnings Call. [Operator Instructions]. After the speakers presentation, there will be a question-and-answer session. [Operator Instructions]. I would now like to hand the conference over to your speaker today, Mr. Simon Latimer. Sir, the floor is yours.SPONSORED:
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