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04.12.21 -- Best Practices For Implementing Decentralized Clinical Trials


04.12.21 Best Practices For Implementing Decentralized Clinical Trials
 
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Is clinical development prepared for the paradigm shift caused by COVID-19? The pandemic has forced the industry to reevaluate how to engage with patients and acquire patient data without direct, in-person access. Biopharmaceutical companies, medical device companies, and CROs from around the world were surveyed to explore the impact on clinical trials in this new paradigm and gain insights into their experiences operationalizing trials in a pandemic. Learn more.
Featured Editorial
By Sam Brown, Nell Haslett-Brousse, Ryan Quinn, and John Theodore, Point B
While the experience design related to the patient is paramount to the adoption of decentralized clinical trial technology, the interrelated experience and incentives for all stakeholders must be fully aligned to realize the full benefits of these platforms. ....

Brian Odwyer , Caroline Keane , Raquel Telfer , Melissa Vadnais , Chuck Drucker , Patrice Hugo , Nathaniel Katz , Christine Moore , Kathy Vandebelt , Michael Murphy , Lesley Freese , Qa Elligo Health Research , Webinar Oracle Health Sciences , Meridian Clinical Research , Case Study Veeva Systems Inc , Seption Group , Elligo Health Research , Advarra Institutional Biosafety Committee , Webinar Perkinelmer Informatics Inc , Oracle Health Sciences , Dawn Niccum , Briano Dwyer , Charlie Fix , Guy Rachmuth , Worldwide Clinical , Institutional Biosafety Committee ,

Arcus Biosciences Presents Updated Data for Etrumadenant in Third-Line Metastatic Colorectal Cancer


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10-Apr-2021
Arcus Biosciences Presents Updated Data for Etrumadenant in Third-Line Metastatic Colorectal Cancer and New Data on its HIF-2α Program at the AACR 2021 Annual Meeting
Phase 1/1b results for the etrumadenant combination demonstrated a 4.2 month PFS, approximately double the 2 months reported for current standard of care therapies in the ≥3L mCRC setting
ARC-9, a randomized Phase 1b/2 platform study, has been initiated to further evaluate etrumadenant-zimberelimab combinations in the 2L, 3L and ≥3L+ mCRC settings
Our novel series of HIF-2α inhibitors, including AB521, a highly-potent molecule with a favorable pharmacokinetic profile, has been described for the first time; we remain on track to initiate clinical development for this program in 2H:21 ....

United States , Katherine Bock , Michael Cecchini , American Association For Cancer Research , Yale Cancer Center , Arcus Biosciences Inc , Arcus Biosciences , Cancer Research , Hypoxia Inducible Factor , Updated Results , Metastatic Colorectal , Bill Grossman , Chief Medical Officer , Assistant Professor , Medical Oncology , Smilow Cancer , Von Hippel Lindau , Private Securities Litigation Reform Act , ஒன்றுபட்டது மாநிலங்களில் , க்யாதரிந் போக் , மைக்கேல் செகீநீ , அமெரிக்கன் சங்கம் க்கு புற்றுநோய் ஆராய்ச்சி , யேல் புற்றுநோய் மையம் , ஆர்கஸ் உயிர் அறிவியல் இன்க் , ஆர்கஸ் உயிர் அறிவியல் , புற்றுநோய் ஆராய்ச்சி ,

Gilead Sciences Announces Fourth Quarter and Full Year 2020 Financial Results


Gilead Sciences Announces Fourth Quarter and Full Year 2020 Financial Results
Diluted EPS of $1.23; Non-GAAP Diluted EPS of $2.19 – Full Year 2020 Year-Over-Year: – Product Sales increased 10% to $24.4 billion, primarily due to Veklury – – Diluted EPS of $0.10; Non-GAAP Diluted EPS of $7.09 – – Returned $5.0 billion of cash to shareholders through dividends and share repurchases – Full Year 2021 Guidance: – Product Sales including Veklury of $23.7 billion to $25.1 billion – – Operating …
– Diluted EPS of $1.23; Non-GAAP Diluted EPS of $2.19 –
Full Year 2020 Year-Over-Year:
– Diluted EPS of $0.10; Non-GAAP Diluted EPS of $7.09 –
– Returned $5.0 billion of cash to shareholders through dividends and share repurchases –
Full Year 2021 Guidance:
– Operating expenses flat to low single-digit percentage decline –
– Non-GAAP Diluted EPS of $6.75 to $7.45 – ....

United States , Foster City , Jacquie Ross , Sonoma Biotherapeutics , Ledipasvir Sofosbuvir , Sofosbuvir Velpatasvir , Complera Eviplera , Novo Nordisk , Vir Biotechnology Inc , Gritstone Oncology Inc , Arcus Biosciences Inc , Gilead Sciences Inc , Janssen Sciences Ireland , European Union , Altera Corp , Racial Equity Community Impact Fund , Asegua Therapeutics , Gilead Public Affairs Department , Gilead Sciences , Pionyr Immunotherapeutics Inc , Tizona Therapeutics Inc , European Commission , Drug Administration , Other International , Exchange Commission , Immunomedics Inc ,