Study identifies protein that could be the key to improving heart attack treatment outcomes

Study identifies protein that could be the key to improving heart attack treatment outcomes
A new study led by researchers at Washington State University has identified a protein that could be the key to improving treatment outcomes after a heart attack.
Published in the
Journal of Biological Chemistry, the research suggests that protein kinase A (PKA) plays a role in heart muscle cell necrosis, a major type of cell death that commonly occurs after reperfusion therapy, the treatment used to unblock arteries and restore blood flow after a heart attack.
Our study has found that turning off a gene that controls this protein activity increased necrotic cell death and led to more heart injury and worse heart function following heart attack in a rodent model. With further research, this discovery could ultimately lead to the development of a small-molecule drug that could intervene in that pathway to limit or prevent heart muscle cell death after reperfusion therapy."

Related Keywords

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