Fatty acid supplementation can lower risk of heart disease in high-risk children Omega-3 supplement alters the lipid profile in the blood of children at high risk for heart disease Fatty acid supplements such as omega-3 can help protect children with high cholesterol from the risk of developing heart disease later in life, reveals a new study. Researchers from the Uniformed Services University of the Health Sciences in Bethesda, Maryland, will present their work virtually this week at the American Physiological Society's (APS) annual meeting at Experimental Biology 2021. Omega-3 Supplements Improve Lipid Profile in Kids With High Cholesterol Previous research has shown that high blood levels of beneficial fatty acids, including omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosapentaenoic acid (DPA) found in seafood, are associated with a lower risk of coronary artery disease and a higher likelihood of healthy aging.