balance. why senator joe manchin says he's a no and is there a hope for historic investments in climate change and childcare? a wide ranging interview with kamala harris about what she says about president biden's agenda and omicron variant. is it the fault against the unvaccinated. >> o'donnell: war on cancer, 50 years since president nixon started fighting the disease and where we go next. father son tee off and a woods' first tournaments since the crash month ago. how the duo fared on the fairway. christmas cheer, a children's hospital making the holidays extra bright for some very special kids. >> o'donnell: good evening, and thank you for joining us. i'm margaret brennan inner norah. we begin with breaking news from the c.d.c. in three weeks, since the first case of that omicrn variant was confirmed here in the u.s., it is now the dominant strain, proving just how quickly the mutation sprendz. omicron variant counts for 73% of new infections, a nearly six-fold increase in only one week. with christmas five days away, there is concern about americans getting on airspace, hitting the road and spreading coronavirus. today, the world health organization urged people to cancel some of their plans. this holiday, surge has rattled financial markets around the world, on wall street the dow fell more than 400 points, its third consecutive day of declines. in europe, cases are surging, and we'll have more on that in a moment. but here in the u.s., new york city continues to be the epicenter of cases and that is where we find nancy chen outside a testing site. good evening to you, nancy. >> reporter: margaret, good evening to you. not only does the c.d.c. now say omicron is the dominant variant but accounts for more nan 90% of the new cases in the new york area as well as parts to have te the country. in new york city, 71% of eligible residents are fully vaccinated. a race against the omicron variant. >> it's very transmissible. it moves fast. we have to move faster. >> reporter: there's a surge and demand for covid tests and the wait could take hours. here's what happened in one line. >> i'm here for the covid test. don't have it. >> reporter: in washington, d.c. the mayor declared a state of emergency nawnd restrictions. >> we will be instituting a d.c. government vaccine mandate to include boosters. >> reporter: but there's positive news today from moderna, the company revealing a new study showing its booster provides a 37 fold increase in antibodies against omicron compared to its two dose regiment. and fresh evidence of covid starling impact on the unvaccinated. a massachusetts health department reports those who have not received a vaccine dose are 31 times more to test positive than those vaccinated with a booster. despite reports of breakthrough cases, the c.d.c. says nationwide those who are unvaccinated are 20 times more likely to die from covid than those boosted. in texas officials announce the first known covid des related to omicron. at houston methodist hospital more than 80% of new symptomatic covid cases are omicron. it took delta three months to reach that level. with omicron, less than three weeks. >> it's blowing delta out of the water in terms of how quickly it has spread. >> how bad could this get? i think omicron is likely to become 100% of the icelets we're seeing in houston easily by the end of the year if not by christmas. >> the director general of the world health organization is now urging people around the globe to consider canceling at least some holiday plans. in houston, dr. wesley long agrees. >> my hope is people saw family members safely during thanksgiving and can delay what would be traditional holiday gatherings maybe till january or february. >> reporter: and americans are still traveling for the holidays. t.s.a. expects to screen 30 million people between now and january 3. here in new york, no word on if the big new year's eve segregation in times square will go on as planned, margaret. >> nancy, thank you. overseas, europe is dealing with a covid surge of their own forcing governments to issue new restrictions and lockdowns. cbs's roxana saberi reports from londony omicron infectious are exploding in numbers. >> reporter: protests against covid restrictions turn tense in london, and in brussels this weekend as demonstrators clashed with police. across europe, countries are battling to contain the omicron variant, heading into christmas. the netherlands has imposed its fourth lockdown closing nonessential shops, bars and restaurants. denmark has shut down theaters, cinemas and miewnlzs. in germany, gatherings could reportedly soon be limited to up to ten people and some travelers arriving in the country must now the u.k., meanwhile, is racing to give all adults a booster shot by the end of the year but is not reimposing severe restrictions yet says british primes boris johnson. >> unfortunately, we will have to reserve the possibility of taking further action to protect the public. >> reporter: one event that won't be going ahead here in london is the annual new year's eve celebration in trafalgar square. mayor sadiq khan tonight announced it will be canceled to reduce the spread of the virus. margaret. >> thank you. the secret piece of president biden's legislative agenda the sweeping $2 trillion spending bill is now on life support. he does not have enough votes from senate democrats to pass it and, tonight, his own party is playing the blame game. we get the latest from cbs's ed o'keefe at the white house. >> reporter: the white house tonight refusing to give up on the president's top legislative priority. >> we are going to continue to take steps and work like hell to get it done. >> reporter: after key democratic senate joe manchin dashed any hopes for its passage sunday. >> i cannot vote to continue with this piece of legislation, i just can't. >> reporter: the decision stunned the white house, they called it a breech of his commitments to the president, but manchin has always been concerned with the size and scope of the president's plan. today the senator blamed white house staff without offering details. >> they drove some things and put some things out that were absolutely inexcusable. >> tax the rich! >> reporter: and the far left for trying to pressure him. >> guess what? i'm from west virginia. i'm not from where they're from and they can just beat the living crap out of people and think they will be submissive per nod. >> reporter: nearly $2 trillion to fight climate change, expand childcare, medicare and the universals pre-k programs put at risk, and it would have renewed an expiring tax credit for nearly 33 million families for children. progressives denounced manchin saying they warned he might do this. >> i really am completely disappointed and disgusted by his reasoning. >> and today they said democratic leaders need to take the kid gloves off in future negotiations. >> of course we have every right to be furiousy r with joe manchin, but it's really up to leadership in the democratic party who made the decision to get us to this juncture and how we're going to move forward. >> reporter: tonight cbs news' learned president biden and senator manchin spoke sunday evening and it went well and senate democrats still plan to debate the president's plan next month when they get back to washington, hoping to force senator manchin not just to express his feelings on the airway but the senate flue. >> an exclusive interview with charles. with a 50/50 split in the senate, build back better was expected to be sent to the president's desk but it is not clear how they'll revive it. do you feel that senator manchin is playing fair with you? he went on television and said no pretty definitively. >> i think the stakes are too high for this to be in any way about any specific individual. >> it's a 50/50 senate though. is, i'm the tie breaker. exactly. the stakes are so high. i refuse to get caught up in thl politics, when the people who are waking up at 3:00 in the morning wore ring how they're going to get by could care less about the politics of d.c. >> so you don't feel betrayed? no, i don't have personal feelings. this is about getting the job done. let's talk with families who say i can't afford to do the basic things that i need to do as a responsible adult, like care for my children, care for my older parents or afford to get life saving medication like insulin. >> how do you do that without senator manchin. >> don't give up. medical experts are projecting we could see as many as a million new infections per day as a result of this omicron variant. is our healthcare system prepared for what's coming? >> we are prepared for it. particularly in the northeast, we're seeing hospitals overwhelmed with delta. inflation is real, it's going to be with us as long as the pandemic dominates. when can you tell the american people this will end? >> we have the power today to go out and, if you've not been boosted, go get boosted, the power today to go and get vaccinated, and that will have an impact on whether we end up tomorrow. >> is it the fault of the unvaccinated? >> i don't think this is a moment to talk about fault. it is no one's fault that this virus hit our shores or hit the world, but it is more about individual power and responsibility and it's about the decisions that everyone has the choice to make, no doubt. >> there are 100,000 russian trops on the border with ukraine. are we going to see a hot war in europe in the next few weeks? >> we are having direct conversations with russia. we are very clear that russia should not invade the sovereignty of ukraine. we are prepared to issue sanctions like you've not seen before. >> does that mean sanctioning vladimir putin directly? >> i am not talking about specific sanction but we are making that clear to him. >> more of our exclusive interview with vice president harris on vbz sundae and "face the nation." we a hearing about the dramatic end of a two month long hostage situation in haiti. the 12 christian missionaries freed last week say they made a daring escape by breaking down a door and hiking across rugged at the rain, part of a group of 17 missionaries including anyone children abducted by a gang demanding a million dollars per hostage. the group says it raised to money to pay the ranszum but still had to escape to freedom. cbs news has still not been able to verify some parts to have the group's story. 50 years ago this week bricksen signed the national cancer act president nixon signed the national cancer act. cancer rates have dropped 27%. dr. jon lapook reports on the progress we've made and how far we have to go. >> when president richard nixon signed the national cancer act just before christmas 1971, cancer was so mysterious and frightening it was often called the big crs. >> you will have the total commitment of government. in the past 25 years the cancer mortality rate increased over 20%. >> it was an all out effort to bring cancer out of the shadows. the law established lshed a national program to study the inner workings of cancer cells and find their weak spots. >> that was really a momentous act. >> dr. lisa deangelis is a neurooncologyist and physician in chief at memorial sloan kettering cancer center. >> the pipeline of discovering continuing today -- >> led to success stores. new treatment harnessed the power of the imhewn system to seek out and destroy the cancer cells. knowing genetics of mutations helps doctors administer treatments. >> diagnosis, melanoma. back then we thought it was 40 diseases, now we think of it as more of 400 diseases, meaning we have had to develop treatments that are unique and specific to each subtype of cancer. >> how were we able to know there were these different types? >> the genomics have given us insight into the many different ways a cancer can form, even when two different cancers look exactly the same under the microscoe. >> that is so key, lisa, right? ere was nothing like this when we started medical school. >> that was 1976 in new york city. dr. deangelis and i were classmates and columbia. >> people were afraid to tell a patient that they had a diagnosis of cancer, family members were always saying don't tell mom, don't tell dad. the treatments were often brutal, quite honestly. and now chemotherapy is given as an outpatient. >> medications now lessen the side effects of chemotherapy and more targeted therapies can kill cancer cells while sparing normal ones but challenges remain. for example pancreatic and brain cancers have especially low survival rates. we're 50 years int into a war that's continuing. that's a long war. >> the war analogy may not have been apt. the concept was we'll be able to treat or eradicate all cancer. but that is not what happened and it's not ever going to happen. >> move forward, we need to improve early detection which is a powerful tool. take colonoscopy which finds and removes polyps before they can turn into cancer. researchers are now using blood tests to find cancer cells at the earliest stages. margaret, i'm optimistic. >> i hope we can all be. thank you, doctor. still ahead, tiger woods on his remarkable comeback to competitive golf. her around the? 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nature's bounty introduces new jelly bean vitamins. good for you nutrients in a tastier for you form. more sweet dreams, more flavorful immune support. new nature's bounty jelly beans. live bountifully. >> brennan: christmas is about giving, family and hope. cbs's jan crawford reports hope is exactly what she found at children's national hospital in washington. >> reporter: nine-month-old mamarch born with a rare heart condition will spend christmas here at children's national hospital in d.c. where he has spent every single day of his life. mom joana commutes from richmond, virginia, two hours away. what are your hopes for christmas? >> what i want for christmas this year is just for him to be okay. >> brennan: about 300 kids will spend their holidays in the hospital. 17-year-old joshua alton will visit the holiday lights in the healing garden. do you have any special hopes fo the new year? >> to be done with cancer next year, not have a tumor on my spine anymore, hopefully, and start walking again. >> reporter: some kids have smaller wishes, too. we've a got a dog, blocks, plastic phone. so santa set up a workshop to make the holidays more normal and ima magical. >> it's fun seeing them open their bags. they get so excited because they didn't know santa could come to the hospital. >> reporter: marvin is too young to believe, but h mom knows there are angels here. >> he know he is well taken care of and i have peace. >> reporter: peace and hope for the new year. jan crawford, cbs news, washington. expwrncht. >> brennan: we'll be right back. look! oh my god... oh wow. ♪ i want my daughter riley to know about her ancestors and how important it is to know who you are and to know where you came from. doesn't that look like your papa? 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>> no. no, it does not. what are you saying? really? >> announcer: "judge judy." you are about to enter the courtroom of you are about to enter the courtroom of judge judith sheindlin. captions paid for by cbs television distribution anita leach is suing her ex-fiancé, robert johnson, for reimbursement of her security deposit and his share of unpaid bills. >> byrd: order! all rise! this is case number 40 on the calendar in the matter of leach vs. johnson. >> judge judy: thank you, byrd. >> byrd: you're welcome, judge. parties have been sworn in. you may be seated. ma'am, have a seat, please. >> judge judy: ms. leach, the defendant was your boyfriend. you signed a lease together in an apartment. >> ex-fiancé. pardon me, judge. >> judge judy: ex-fiancé. >> pardon me. yes. >> judge judy: you signed the lease together in an apartment. he left. the lease was broken. you want him to reimburse you for your lost security deposit. the defendant says that you kicked him out, that you lost the security deposit because you got drunk and you broke a window. am i correct? and he has a counterclaim because he said you caused damage to his car purposefully. so, when did you move in together? >> we moved in december the 30th, 2014. >> judge judy: and when did you move out, sir? >> january of 2016. >> judge judy: you renewed the lease. did you renew the lease? >> [ stammers ] >> judge judy: don't look at her. >> automatic -- >> judge judy: you're looking at her like she's your wife. >> [ chuckles ] >> we were -- >> judge judy: "what should i say?" [ laughter ] >> i thought i was gonna be his wife, your honor. i'm sorry. i'm didn't mean to... >> judge judy: okay. i don't care, but, you know, don't look at her. >> okay. >> judge judy: if you rely on her that much, you should still be together.