welcome to this bbc news coronavirus special programme. ministers have sought to reassure people about the roll out of the coronavirus vaccine amid a reduction in supply which means most people in their 40s will now have to wait till may for a jab. the government insists it will still offer all adults their first dose by the end ofjuly, but in the commons earlier today the health secretary confirmed supplies would become tighter in the weeks ahead. the bbc understands a delay in the delivery of 5 million doses of the oxford—astrazeneca jab from in india is one factor. but matt hancock said no vaccine appointments booked would be cancelled and people would still get their second dose as planned. katharine da costa reports. this vaccination centre in south—west london is one of hundreds around the country that so far help to give a dose to around half of all adults in england. having opened up appointments for the over 50s, the nhs in england is now being told not to offer vaccines to younger age groups throughout april because of significant supply issues. but the health secretary has insisted the roll—out will continue as planned. there will be no weeks in april with no first doses. there will be no cancelled appointments as a result of supply issues, second doses will go ahead as planned. most importantly, the vaccine data published yesterday showed the life—saving impact of this vaccine. it's not just that the vaccines are safe, it's that they make you safe. the uk had been expecting 10 million doses of the oxford astrazeneca vaccine from india this month, but only half has arrived. the serum institute has spoken of the pressure it's under. to provide both international and domestic supplies. we are hoping very much that all other vaccine producers scale up because right now the pressure on serum institute is unprecedented. we're being tugged at by different governments in the world. we need to support astrazeneca. for the countries they need to supply vaccines to. and we are being literally forced to supply as much product to the indian government as well. astrazeneca said its uk supply has not been affected. pfizer, which produces its vaccine in belgium, said deliveries to the nhs are also on track. and supplies of moderna are expected some time in the spring. but experts say the manufacture and supply of vaccines is a delicate process. of course, we're dealing with unprecedented demand. we are trying to get the same products to the whole world all at the same time, and these supply chains have high quality characteristics so we do want these to be the highest quality out there. there is very strict testing and authorisations from the different health authorities. the government's warned uk supplies could be lumpy. you can see the supply of doses can fluctuate from week to week. some of those advising the government on the roll—out are concerned delays could impact efforts to tackle the virus. phase two is really important, actually, and if we can't do that as spring progresses, we will be left in a position where we are continuing to have to have lockdowns and so on to control the spread of the virus. despite the setback, the government is still confident it can meet its target for offering all adults a jab by the end ofjuly. it says the road map for easing restrictions is still on track but it will no doubt come as a blow for the over 40s who will have to wait for their invite a little while longer. katharine da costa, bbc news. our correspondent rajini vaidyanathan is in northern india. pa rt part of the issue with the supply problem of vaccines in the uk is as a result of manufacturing where you are. explain exactly what is may be happening. 50. are. explain exactly what is may be ha henin, .,, are. explain exactly what is may be hamenin, . happening. so, as we saw in that re ort, happening. so, as we saw in that report. the _ happening. so, as we saw in that report. the uk — happening. so, as we saw in that report, the uk government - happening. so, as we saw in that - report, the uk government announced at the start of march that it was ordering 10 million doses of the oxford astrazeneca jab from the serum institute, which is the world's largest vaccine supplier. what we have now been told, and i have spoken to somebody from the serum institute this evening, and he said 5 million of the doses have been sent, but there will be a delay on the other 5 million. what the spokesperson said it is, we will try to supply more later based on the current situation and the requirements for india's immunisation programme. clearly there is a lot of pressure to supply there is a lot of pressure to supply the domestic market here in india. but india's foreign minister in parliament yesterday told parliament that 72 countries have been supplied with indian made covid vaccinations. india prides itself on being able to send its indian made vaccines around the world, but the foreign minister said availability will always depend on demand at home. as covid cases are now rising in india for the first time in months at a level we have not seen since december, domestic demand is clearly a big issue here. domestic demand is clearly a big issue here-— domestic demand is clearly a big issue here. , ., , , ., issue here. does that suggest that de endin: issue here. does that suggest that depending on _ issue here. does that suggest that depending on domestic _ issue here. does that suggest that depending on domestic demand i depending on domestic demand supplies around the world, including to the uk, can always fluctuate potentially? i to the uk, can always fluctuate potentially?— to the uk, can always fluctuate otentiall ? ~ . , ., potentially? i think that my dear. 72 countries. _ potentially? i think that my dear. 72 countries, a _ potentially? i think that my dear. 72 countries, a huge _ potentially? i think that my dear. 72 countries, a huge number, - potentially? i think that my dear. | 72 countries, a huge number, and some of those are donations made by the indian government to some of its neighbours, for example bangladesh and sri lanka. we have also been hearing that some of the supplies to nepal are potentially being delayed. it is notjust the uk. the ceo of the serum institute, who you saw in the serum institute, who you saw in the report, also said recently at a world bank event that some of the delays could also be more generally put down to the fact that the us now has an export ban on certain raw materials that their company uses to make vaccines. i thought it was quite interesting. the administration has brought these export bans in, but they are impacting companies like the serum institute of india. that could impact global vaccine delivery as well. 50 impact global vaccine delivery as well. impact global vaccine delivery as well, ., impact global vaccine delivery as well. . , , well. so there are problems with the su -l well. so there are problems with the supply chain — well. so there are problems with the supply chain further _ well. so there are problems with the supply chain further down _ well. so there are problems with the supply chain further down the - well. so there are problems with the supply chain further down the line, l supply chain further down the line, so the viles, the stoppers for the vials, the plastic lining for the drums the vaccine is made and, though supply problems are having an effect on india's ability to produce the number of vaccines everyone hoped? the number of vaccines everyone ho ed? ., , the number of vaccines everyone hoed? . ,. ., , ., hoped? that is certainly what the ceo said at _ hoped? that is certainly what the ceo said at a _ hoped? that is certainly what the ceo said at a few _ hoped? that is certainly what the ceo said at a few weeks - hoped? that is certainly what the ceo said at a few weeks ago. - hoped? that is certainly what the ceo said at a few weeks ago. he | ceo said at a few weeks ago. he raised concerns about this export ban that has been brought in by the us administration. another factor as well is there was a fire at the serum institute and insiders say this is also set back production. there are lots of factors, but the overriding political issue as well as making sure that domestic supplies are available. as i said, covid cases have been low in recent months but they are spiking in certain parts of india and the indian government has expanded its immunisation programme recently, but there are also reports that as early as next week it could open eligibility to an even wider age group, maybe the over 50s are the over a0 fives. anyone over the age of 60 could get the vaccine and a5—year—olds with pre—existing conditions. there is huge demand here. the immunisation programme is the largest vaccination programme in the largest vaccination programme in the world and it will always come down to as well as supply chain issues and everything else, making sure that indian domestic demand is met and that is a challenge everywhere in the world. how many of these vaccines do you stand out and how many do you keep for your own country? how many do you keep for your own count ? ., ., how many do you keep for your own count ? ., ,, ,, thank you. and we've just had the latest figures. the uk has reported 95 new deaths within 28 days of a positive test. the figures are still going in the right direction. the figures are still going in the right direction. 6,303 new covid—i9 cases have also been reported today. those are the figures on the screen. we have also got 25.7 million people have also received their first dose. those are the latest figures on the vaccination programme. 1.87 million have received their second dose. the big question is how might those figures be affected if there is a delay in vaccinations because of the supply problems throughout the next few weeks? let's get more from our political correspondent damian grammaticas. the government is anxious to reassure people, those people who have made appointments already, that they will be able to get their vaccines?— they will be able to get their vaccines? , , ., they will be able to get their vaccines? , , . ., vaccines? yes, they have said all existin: vaccines? yes, they have said all existing appointments _ vaccines? yes, they have said all existing appointments will - vaccines? yes, they have said all existing appointments will be - existing appointments will be honoured and will continue to happen. the letter that was sent out yesterday from nhs england to all of those hospitals, the vaccine centres, the gp surgeries, who are performing these vaccinations, had said take no new bookings through the month of april. what the health secretary has said today is that should still mean it is possible, and they will continue to do, all the second doses that people are now due. people who had first dose is ten or 12 weeks ago and are coming due now will continue, because it is important they get those on time. equally, all the priority, or any remaining priority cases, people with particular health conditions, things like that, should be able to get them as well. also the over 50s. but the health secretary did say in the comments that should mean there will continue to be first dose is being given as well through april, however it does also mean that because of these constraints on supply that things will have to go a bit slower for a few weeks. 50 it supply that things will have to go a bit slower for a few weeks.- bit slower for a few weeks. so it is the over 40s _ bit slower for a few weeks. so it is the over 40s we _ bit slower for a few weeks. so it is the over 40s we are _ bit slower for a few weeks. so it is the over 40s we are talking - bit slower for a few weeks. so it is| the over 40s we are talking about, the over a0s we are talking about, the over a0s we are talking about, the roll—out of vaccinations for them, that potentially could slow in them, that potentially could slow in the next three to six weeks? it seems so because at the moment what we have is this call that went out yesterday expanding the programme to the over 50s. they are dropping down through the age ranges and it is now anyone 50 and over has been invited to come forward. but it appears it will probably pause at that point while the roll—out continues in that group and then the government assesses the ongoing vaccine supply. it is a sort of moving picture all the time. the difficulty seems to be they have got bumper supplies now, but for a couple of weeks ahead it is looking a little bit more constrained. is is looking a little bit more constrained.— is looking a little bit more constrained. , ., ., constrained. is that government convinced it _ constrained. is that government convinced it can _ constrained. is that government convinced it can meet _ constrained. is that government convinced it can meet its - constrained. is that governmenti convinced it can meet its overall target of all adults by the end of the summer?— target of all adults by the end of the summer? . , ., , _ the summer? that is what they say, and not even _ the summer? that is what they say, and not even by _ the summer? that is what they say, and not even by the _ the summer? that is what they say, and not even by the end _ the summer? that is what they say, and not even by the end of- the summer? that is what they say, and not even by the end of the - and not even by the end of the summer. mid—july is the target for all adults. summer. mid—july is the target for alladults. by summer. mid—july is the target for all adults. by mid april is the target for all over 50s. it seems to be well on track for the over 50s. confidence is what they are expressing. of course we have to see what happens with the supplies. as you are hearing, that depends on what happens with producers and the situation with a pandemic in other countries. ., ., situation with a pandemic in other countries. ., ,, , ., ., countries. 0k, thank you. damian grammaticas- _ a review by the european union's medicines regulator has concluded the oxford—astrazeneca covid—19 vaccine is "safe and effective". the european medicines agency said the benefits of the vaccine outweigh the risks. it follows the suspension of the jab by several eu nations. the world heatlh organisation has underlined the urgent need for vaccines, as it says more than 20,000 people are dying each week in europe from covid—19. speaking at a news conference in the past hour, the regulator's executive director, emer cooke, said that the committee would continue to study possible links between rare blood clots and the vaccine. our expert committee on the safety of medicines, the pharmaceutical vigilance risk committee, has now come to a conclusion on the review of cases of blood clots in people vaccinated with astrazeneca's covid—19 vaccine. the committee has come to a clear scientific conclusion. this is a safe and effective vaccine. its benefits in protecting people from covid—19 with the associated risks of death and hospitalisation outweigh the possible risks. the committee also concluded that the vaccine is not associated with an increase in the overall risk of thromboembolic events or blood clots. now, during the investigation and review we began to see a small number of cases of rare and unusual but very serious clotting disorders and this then triggered a more focused review. based on the evidence available and after days of in—depth analysis of lab results, clinical reports, autopsy reports and further information from the clinical trials, we still cannot rule out definitively a link between these cases and the vaccine. the european medicines agency. our health correspondent nick triggle is with me. nick, bring us up to date. no, it is very much what experts expected. when you vaccinate millions of people, it is very much expected that some people will die or become ill after being vaccinated, but that does not mean that the vaccination caused that, it is just coincidence, that these things would happen naturally anyway. what the regulators do, both the eu regulator and the regulator in the uk have been looking at this, is to monitor the number of adverse events, to see if it is higher than normal levels, after vaccination. and as we have heard, the numbers of blood clots being seen generally are actually lower than you would expect. but there have been a number of rare cases of blood clots in the brain. there have been 18 of these across europe, five of them in the uk. but because they're so rare, it is hard to say whether they are above or below the normal expected thresholds. so, that means the regulators can't rule it out, and they have carried out detailed investigations into the individual cases, checking their medical history of the patients involved, to investigate that further, but they say that the benefits clearly outweigh the risk. and that is because, if we look at the 18 cases, thatis because, if we look at the 18 cases, that is out of around 20 million astrazeneca vaccinations done, so, one in a million chance. if you are over the edge of 75 and you become infected with covid, you have got a one in nine chance of dying. and if you are an a0s, much younger, you have still got a one in 1000 chance of dying. so, we know that this vaccine is highly effective. so even if it is causing these rare blood clots, and there is no evidence to suggest that it is, it would still be worth taking. and that is why the message is clear, vaccination should continue, people can be confident in the vaccine. but continue, people can be confident in the vaccine-— the vaccine. but the ema also said that they want _ the vaccine. but the ema also said that they want to _ the vaccine. but the ema also said that they want to put _ the vaccine. but the ema also said that they want to put out - the vaccine. but the ema also said that they want to put out an - that they want to put out an advisory, a warning, two doctors and those people who will be administering the vaccine, what form would that take, and roughly what might the wording be? well. would that take, and roughly what might the wording be?— would that take, and roughly what might the wording be? well, we are et to hear might the wording be? well, we are yet to hear the _ might the wording be? well, we are yet to hear the exact _ might the wording be? well, we are yet to hear the exact wording, - might the wording be? well, we are yet to hear the exact wording, but l yet to hear the exact wording, but what is going to be essential now, going forward, is very close monitoring of these cases, any cases of this rare blood clot getting reported in immediately, because what the regulators have had to go and do is to go back and ask for information and go through a lot of records to check how many cases of this blood clotting there have been. so, this will now be routinely reported into the regulators in europe and in the uk. on top of that, the regulator in the uk has issued some advice to the public, and they are saying, if people have and they are saying, if people have a headache for more than four days, after vaccination, a headache for more than four days, aftervaccination, or a headache for more than four days, after vaccination, or bruising away from the site where the vaccination was given, they should seek medical attention and ask advice from a doctor. . ., ., ., attention and ask advice from a doctor. w ., ,, , ., doctor. 0k, nick triggle, thank you for that. dr dan bunstone is an nhs gp and chief medical officer at push doctor. thanks forjoining us. the uk regulator, the eu regulator, is saying that the astrazeneca vaccine is safe as far as they are concerned, that makes sense to you? oh, absolutely right. as was talked about before, it reinforces what we all long suspect, and it is great news now that we can really get on the back of getting increasing vaccination numbers done. we've made really good progress the country. primary care has massively stepped up primary care has massively stepped up and we've made some really good progress with some really good vaccination in the nation, which is a really strong position to be in. what happens if a patient turns up and says i am not having the astrazeneca, because it could be a bit iffy, i want moderna, one of the other ones? {iii bit iffy, i want moderna, one of the other ones?— other ones? of course, there is alwa s other ones? of course, there is always the _ other ones? of course, there is always the element _ other ones? of course, there is always the element of - other ones? of course, there is always the element of patient l other ones? of course, there is - always the element of patient choice and we are never going to pin someone down and force a vaccination on them. that said, i think it is about a conversation to make sure that they are fully versed with the facts. as we know, to reiterate what has been said, the astrazeneca vaccine is safe. the rha have said that, and the european agency as well, so that we know it is safe, and of course, much safer than contracting covid.— and of course, much safer than contracting covid. what are your concerns now, _ contracting covid. what are your concerns now, given _ contracting covid. what are your concerns now, given the - contracting covid. what are your . concerns now, given the suggestion that there could be supply shortages through the next three or four weeks? i through the next three or four weeks? ., , through the next three or four weeks? ~ , ., ., , weeks? i think it is going to be tric , of weeks? i think it is going to be tricky, of course. _ weeks? i think it is going to be tricky, of course. i— weeks? i think it is going to be tricky, of course. i think - weeks? i think it is going to be tricky, of course. i think if - weeks? i think it is going to be tricky, of course. i think if we i weeks? i think it is going to be i tricky, of course. i think if we had plenty of vaccination, we would be able to get on with it, and there are always going to be risks there. i know the teams that nhs england are doing what they can to get the supply through, which is a really strong position to be in. we have always been good at flexing on what we are given and having a very reactive service, booking in patients as when the supplies come through. we will always strive to do that and we will work with what we are given. that and we will work with what we are riven. ., ., that and we will work with what we are riven. ., . ,, that and we will work with what we are riven. ., ., i. ., ., that and we will work with what we are riven. ., . ,, ., ., ., are given. how are you managing to net are given. how are you managing to get through — are given. how are you managing to get through the _ are given. how are you managing to get through the cohorts, _ are given. how are you managing to get through the cohorts, are - are given. how are you managing to get through the cohorts, are you - are given. how are you managing to. get through the cohorts, are you now starting on the over fifties? yes. starting on the over fifties? yes, so, starting on the over fifties? yes, so. we've _ starting on the over fifties? yes, so, we've made _ starting on the over fifties? yes, so, we've made some _ starting on the over fifties? yes, so, we've made some great - starting on the over fifties? ye: so, we've made some great progress. i am based up in warrington and we have done a huge number of vaccinations, we are now down to our over—50s, that is what we are going to start working towards. we've done 65,000 vaccines and it has been a completely collaborative effort, everybody working together. and i know that is replicated across the country. a lot of work which has enabled us to do this so well has been because of primary care networks and because of support organisations like nhs confederation, really providing that support to bring us all together. and what is the scale of vaccine hesitancy, have you seen it perhaps diminish as more and more people have taken up the vaccine and people have taken up the vaccine and people have seen that it is safe? i ififiiiii have seen that it is safe? i will tell you. _ have seen that it is safe? i will tell you. it _ have seen that it is safe? i will tell you, it was _ have seen that it is safe? i will tell you, it was a _ have seen that it is safe? i will tell you, it was a real - have seen that it is safe? i will tell you, it was a realjoy - have seen that it is safe? i will tell you, it was a realjoy to . have seen that it is safe? i will l tell you, it was a realjoy to start the vaccinations way back in december. people had been in lockdown for a long period, they had been vulnerable, they were worried about things, and actually being able to give them the vaccination, to start that process of giving them confidence, to start the freedom again, to be able to get out of the house, was an amazing position to be in, and no smallamount house, was an amazing position to be in, and no small amount of emotion behind that, i can tell you. that in, and no small amount of emotion behind that, i can tell you.— behind that, i can tell you. that is really good _ behind that, i can tell you. that is really good to _ behind that, i can tell you. that is really good to hear, _ behind that, i can tell you. that is really good to hear, thanks - behind that, i can tell you. that is really good to hear, thanks for - really good to hear, thanks for joining us. let's speak now to the scottish health secretary, jean freeman. thanks for being with us, the european regulator now says the vaccine is safe, the british regulator is saying that as well, are you confident in scotland? yes. are you confident in scotland? yes, we are. are you confident in scotland? yes, we are- we — are you confident in scotland? yes, we are- we also — are you confident in scotland? yes, we are. we also have _ are you confident in scotland? yes, we are. we also have of— are you confident in scotland? yes, we are. we also have of course the advice _ we are. we also have of course the advice of _ we are. we also have of course the advice of our— we are. we also have of course the advice of our own chief medical officer, — advice of our own chief medical officer, so we will make sure that that is— officer, so we will make sure that that is communicated widely, it is good _ that is communicated widely, it is good news — that is communicated widely, it is good news. we had confidence in the astrazeneca vaccine, as well as the pfizer— astrazeneca vaccine, as well as the pfizer vaccine. and we just need to make _ pfizer vaccine. and we just need to make sure — pfizer vaccine. and we just need to make sure that our vaccinating teams have all— make sure that our vaccinating teams have all the _ make sure that our vaccinating teams have all the information that they need _ have all the information that they need to— have all the information that they need to be able to answer any questions _ need to be able to answer any questions from patients coming forward — questions from patients coming forward for the vaccine. but as with your previous contributor, we've had extraordinarily high uptake so far, we have _ extraordinarily high uptake so far, we have in— extraordinarily high uptake so far, we have in scotland as i suspect elsewhere, a strong track record in public— elsewhere, a strong track record in public support for vaccination, our flu vaccine — public support for vaccination, our flu vaccine programme, our childhood vaccine _ flu vaccine programme, our childhood vaccine programme, so we are not seeing _ vaccine programme, so we are not seeing large levels of hesitancy, but people have perfectly reasonable question— but people have perfectly reasonable question is that they want to ask, and we _ question is that they want to ask, and we are — question is that they want to ask, and we are ready to be able to answer— and we are ready to be able to answer those. but and we are ready to be able to answer those.— and we are ready to be able to answer those. but there is that fear, answer those. but there is that fear. isn't _ answer those. but there is that fear, isn't there, _ answer those. but there is that fear, isn't there, of— answer those. but there is that fear, isn't there, of supply - fear, isn't there, of supply shortages coming down the track, the uk is not getting the numbers of vaccine vials as it expected from india, supply, the suggestion is from the government that it was always going to be bumpy, but we've got less than half the supply that we thought we would be getting from the indians? 50. we thought we would be getting from the indians? ., ., ., the indians? so, we are in scotland between 400,000 _ the indians? so, we are in scotland between 400,000 - _ the indians? so, we are in scotland between 400,000 - 500,000 - the indians? so, we are in scotland i between 400,000 - 500,000 doses between a00,000 — 500,000 doses short of what we expected in the next few weeks. we do expect those to come, though, they arejust next few weeks. we do expect those to come, though, they are just going to come, though, they are just going to come, though, they are just going to come later, that is my understanding. the fact is, in a programme like this, across the uk and here in scotland, it is bumpy, it has been from day one. what we have to have is really close modelling between what we know is coming in with supply and how we schedule appointments. and even though it is tight, we fully expect to be able to meet our commitment, which is to be able to offer the vaccine appointment to everyone over 50 by mid april. and also, of course, the number of second doses is also increasing. so, we've now hit over the 2 million mark of first doses, 192,002nd doses. it is a constant exercise, i look every single day at the numbers in terms of supply and booked appointments, what we expect to do in the coming every week. day, as i said, and believe me our first minister takes a lot of interest in this as well. so we track it really carefully. but at this point, even with that delay in those doses coming through from astrazeneca, we still believe that we will be able to meet that commitment, although it is tight, but that is everyone over 50 and there was really criticaljcvi priority groups 1—9. 50. there was really criticalevi priority groups 1-9.- there was really criticalevi priority groups 1-9. so, you say it's tight. _ priority groups 1-9. so, you say it's tight. are — priority groups 1-9. so, you say it's tight, are you _ priority groups 1-9. so, you say it's tight, are you confident - priority groups 1-9. so, you say| it's tight, are you confident that you can give all those people who are coming to, what is it 6—8 weeks, possibly 9—10 weeks before their second dose, you are confident that they will all be able to get their second dose?— second dose? sorry, i lost the second dose? sorry, i lost the second part — second dose? sorry, i lost the second part of _ second dose? sorry, i lost the second part of your _ second dose? sorry, i lost the second part of your question. | second dose? sorry, i lost the i second part of your question. are ou second part of your question. are you confident _ second part of your question. are you confident that those people coming up to the period where they need to get their second dose, you will have enough vaccine for them to get that? will have enough vaccine for them to net that? ~ , will have enough vaccine for them to netthat? ~ , ,, , get that? absolutely. second doses are a real priority. _ get that? absolutely. second doses are a real priority. so, _ get that? absolutely. second doses are a real priority. so, what - get that? absolutely. second doses are a real priority. so, what we - are a real priority. so, what we have said to our vaccination teams is, you've got two priorities. we need to make sure that we can offer everyone over 50, and we are now in that group of those over 50, up to 59, where it is 7a% of 60—6a —year—olds, so we are chugging along well. but the priority has to be to get those appointments out to the over—50s, but also to make absolutely sure that the second doses are delivered within the 12 weeks. that's really critical, because the whole point of this exercise is maximum protection to those who are most vulnerable to serious illness and death from this particular a virus.— particular a virus. indeed, scottish health secretary _ particular a virus. indeed, scottish health secretary jeane _ particular a virus. indeed, scottish health secretary jeane freeman, i health secretary jeane freeman, thank health secretaryjeane freeman, thank forjoining us. we can talk now to nick triggle. we will be going to westminster to get the latest update with the prime minister, and the focus will be on this supply shortage. in scotland, we heard the health secretary there saying that they have enough doses for now, but it is going to be tight? for now, but it is going to be ti . ht? , for now, but it is going to be tiht? , ., tight? indeed. if we 'ust look at toda 's tight? indeed. if we 'ust look at today's figures, _ tight? indeed. if we 'ust look at today's figures, for _ tight? indeed. if we just look at today's figures, for the - tight? indeed. if we just look at| today's figures, for the numbers tight? indeed. if we just look at. today's figures, for the numbers of vaccinations that were done yesterday, this illustrates the challenge the uk is facing. there were a62,001st doses given, but there were also 120,002nd doses. that is the highest number of second doses so far. as we get into april, we will need to do more and more second doses. during april, they have to do 12,000,002nd doses, so, 3 million a week. so far, during the past month, we have only been doing between two million and 3 million vaccinations in total. so that is why the uk government was so keen to get extra supplies in, the supplies from india, to help relieve some of that pressure and ensure they can do first doses as well as second doses. we have heard from the health secretary, matt hancock, today that they will still be doing some first doses, butjust not as many as perhaps was hoped a week or so ago, when they were really talking about getting into that age group, a0— to 50—year—olds. they are going to have to wait a little bit longer, but some will still get it, we are being told, and the target to offer every aduu told, and the target to offer every adult a vaccination by the end of july should still be met, and therefore, the restrictions, the easing of lockdown, should still continue as the government has set out. . �* , , continue as the government has set out. ., �* , , , ., continue as the government has set out. , ,., ,�* out. that's the big question, isn't it? how could _ out. that's the big question, isn't it? how could the _ out. that's the big question, isn't it? how could the delay _ out. that's the big question, isn't it? how could the delay in - out. that's the big question, isn't. it? how could the delay in supplies affect the unlocking of the restrictions at the moment? and the fact that it's the most vulnerable who have already received at least one dose, that gives the government to little bit of slack, perhaps? it does. vaccination does help reduce the spread of infection, so, if we don't vaccinate these younger groups as quickly as we hoped or possibly could have, a week ago, that perhaps will mean keeping infection levels low will be slightly harder. however, the over 50 age groups, 99% of covid deaths have been in that age group. the overwhelming majority of hospital admissions have been in that age group. so in terms of that serious illness, which after all is what we are most concerned about, the progress that the uk has made puts us in a very strong position, evenif puts us in a very strong position, even if there are delays with further vaccinations. what is going to be crucial is obviously we are expecting another a million — 5 million doses from india. the hope is that that will arrive within four weeks. but obviously the supply chain is fragile and until that shipment arrives, i don't think anyone will be confident, 100% confident. the other vaccine that is coming down the line is maternal, it's been approved by the regulator in the uk. the uk government has ordered 17 million doses of that, and the first few million doses i have been told will start arriving after easter. so, that should also help us. after easter. so, that should also hel us. . v after easter. so, that should also hel us. ., �*, ., , , help us. that's really interesting come, help us. that's really interesting come. from _ help us. that's really interesting come, from you, _ help us. that's really interesting come, from you, nick. - help us. that's really interesting come, from you, nick. let's - help us. that's really interesting| come, from you, nick. let's turn help us. that's really interesting i come, from you, nick. let's turn to damian grammaticus, who is at westminster from us. damian grammaticus, who is at westminsterfrom us. —— for us. we arejust westminsterfrom us. —— for us. we are just counting down to the briefing from the prime minister, which is coming up. damian grammaticus, the roll—out of the vaccination programme, on any measure, has been a success here in the uk, this is probably one of the first bumps in the road that the government has had to deal with, how are they handling the messaging of all of this? ~ , ., , are they handling the messaging of all of this? ~ , .,, i. all of this? well, it is, as you sa , all of this? well, it is, as you say. clive- — all of this? well, it is, as you say, clive. there _ all of this? well, it is, as you say, clive. there has - all of this? well, it is, as you say, clive. there has been i all of this? well, it is, as you say, clive. there has been al all of this? well, it is, as you i say, clive. there has been a lot all of this? well, it is, as you - say, clive. there has been a lot of focus _ say, clive. there has been a lot of focus on _ say, clive. there has been a lot of focus on just — say, clive. there has been a lot of focus onjust how say, clive. there has been a lot of focus on just how successful this has been — focus on just how successful this has been so far and how the uk is at the forefront of vaccinating people, the forefront of vaccinating people, the roll—out here has happened... i am the roll—out here has happened... am sorry, i am the roll—out here has happened... i am sorry, i am going to cut in because we are hearing from the prime minister, he isjust arriving at the podium. good afternoon, i am joined byjane raine and chris whitty. our road map to freedom depends on the continued success of our vaccination programme and so it is reasonable for people to want to be continually reassured, not only that our vaccines are safe and effective, but also that we have the supply that we need. i want to address both points today, especially in the light of concerns you may have heard in some other countries about the oxford astrazeneca vaccine. first, the independent medicines and health care products regulatory agency has reviewed the evidence, as it does every week, and they have confirmed that the benefits of the vaccine in preventing covid far outweigh any risks and people should continue to get their vaccine when asked to do so. june also a little bit more about that in a moment. it is also very important for our european friends that today the european medicines agency has come to a clear scientific conclusion, and i quote, this is a safe and effective vaccine. we also saw yesterday the evidence from public health england that a single dose of either vaccine provides 60% protection against getting covid and reduces the chances of hospitalisation by 80%, and the risk of death by 85%. the oxford jab is safe and the pfizer job is safe. the thing that is not safe is catching covid, which is why it is so important that we all get ourjabs as soon as our turn comes and as it happens i am getting mine tomorrow and the centre where i am getting it is currently using the oxford astrazeneca vaccine for those receiving their first dose and that is the one i will be having. let me also assure you that if you come forward after receiving your letter, we have the jabs for you. we have always said that a vaccination programme of this pace and this scale some interruptions in supply are inevitable. it is true that in the short term we are receiving fewer vaccines than we had planned for a week ago. that is because of a delay in shipment from the serum institute who are doing a herculean job in producing vaccines in such large quantities. because of a batch we currently have in the uk that needs to be retested as part of our vigorous safety programme. as a result we will receive slightly fewer vaccines in april than in march, but that is still more than we received in february. and the supply we do have will still enable us to hit the targets we have set. that means that by the 15th of april we will be able to offer a first dose to all of you who are over 50, as well as those under 50 who are clinically vulnerable. we will have the second doses that people need within the 12 week window, which means around 12 million people in april. and we will still offer a first dose to every adult by the end ofjuly. so there is no change to the next steps of the road map. we have now vaccinated over 25 million people across our entire united kingdom, more than the entire population of many countries. our progress along the road to freedom continues unchecked. we remain on track to reclaim the things we love, to see our families and friends again, to return to our local pubs, gyms and sports facilities, and of course our shops. all, of course, as long as the data continues to go in the right direction and we meet our four tests. and the way to ensure that this happens is to get thatjab when your turn comes, so let's get thejob done. thank when your turn comes, so let's get the job done. thank you very much. when your turn comes, so let's get thejob done. thank you very much. i will now hand over tojune. goad will now hand over to june. good afternoon- _ will now hand over to june. good afternoon. the _ will now hand over to june. good afternoon. the mhra _ will now hand over to june. good afternoon. the mhra has - will now hand over tojune. (limp. afternoon. the mhra has been carrying out robust safety vigilance in tandem with the covid—19 vaccination programme. our role is to continually monitor safety during widespread use of a vaccine, to confirm that they are performing as expected, to identify any new side effects that arise, and to ensure that the benefits continue to outweigh the risks. we have been able to gather a large amount of data on the safety profile of the available vaccines and have done a rigorous, scientific review of all the available data with regards to suspected blood clots. our review, alongside a critical assessment of leading independent scientists in the commission on human medicines, shows that there is no difference that blood claws in vanes are occurring more than would be expected in the absence of vaccination for either vaccine. the public can have every confidence in the thoroughness of our review. we have also received five reports of a different, a rare form of blood clot in the cerebral sinuses, cerebral sinus pain thrombosis, occurring together with lowered blood platelets shortly after vaccination with the covid-19 platelets shortly after vaccination with the covid—19 vaccine astrazeneca. this type of blood clot can rarely occur naturally in unvaccinated people, as well as with people with covid—19 disease. a further review of these events is ongoing, but a causal relationship with the vaccine has not yet been established. the rate of occurrence of these events among the 11 million people vaccinated is extremely rare. while we continue to investigate these cases as a precautionary measure, we would advise anyone with a headache that lasts more than four days after vaccination, or bruising beyond the site of vaccination after a few days, to seek medical attention. we will communicate further on the outcome of this further on the outcome of this further review when it is complete. the mhra assess this data alongside the benefits of the vaccine in preventing covid—19, with its associated risk of hospitalisation and death and determine that the benefits firmly remain to outweigh the risks. so you should continue to receive your vaccine when you get the call or the second dose as soon as you are contacted. i want to end tjy as you are contacted. i want to end by expressing our sincere gratitude to those who have sent reports to the mhra and remind everyone that you can report, and you should report, all suspected side—effects to covid-19 report, all suspected side—effects to covid—19 vaccines through the coronavirus yellow card scheme. thank you, prime minister. thank you very much. — thank you, prime minister. thank you very much. june- _ thank you, prime minister. thank you very much, june. let's _ thank you, prime minister. thank you very much, june. let's go _ thank you, prime minister. thank you very much, june. let's go to - thank you, prime minister. thank you very much, june. let's go to chris. . very much, june. let's go to chris. let's go to jane from buckinghamshire. let's go to jane from buckinuhamshire. ,., ., ., ., ., �* , buckinghamshire. good afternoon. by the uk able to — buckinghamshire. good afternoon. by the uk able to provide _ buckinghamshire. good afternoon. by the uk able to provide stats _ buckinghamshire. good afternoon. by the uk able to provide stats to - the uk able to provide stats to prove — the uk able to provide stats to prove that _ the uk able to provide stats to prove that the _ the uk able to provide stats to prove that the astrazeneca - the uk able to provide stats to - prove that the astrazeneca vaccine is safe _ prove that the astrazeneca vaccine is safe and — prove that the astrazeneca vaccine is safe and eliminate _ prove that the astrazeneca vaccine is safe and eliminate the _ prove that the astrazeneca vaccine is safe and eliminate the current. is safe and eliminate the current fears— is safe and eliminate the current fears of— is safe and eliminate the current fears of blood _ is safe and eliminate the current fears of blood clots _ is safe and eliminate the current fears of blood clots in _ is safe and eliminate the current fears of blood clots in the - is safe and eliminate the current fears of blood clots in the eu - is safe and eliminate the current. fears of blood clots in the eu stop i am fears of blood clots in the eu stop i am passing _ fears of blood clots in the eu stop i am passing that— fears of blood clots in the eu stop i am passing that straight- fears of blood clots in the eu stop i am passing that straight back. fears of blood clots in the eu stop i am passing that straight back to| i am passing that straight back to june and — i am passing that straight back to june and then _ i am passing that straight back to june and then to— i am passing that straight back to june and then to chris. _ i am passing that straight back to june and then to chris. yes, - i am passing that straight back to june and then to chris.— i am passing that straight back to june and then to chris. yes, we can. we are committed _ june and then to chris. yes, we can. we are committed to _ june and then to chris. yes, we can. we are committed to transparency. | june and then to chris. yes, we can. i we are committed to transparency. we publish every week all suspected adverse drug reaction reports we receive and our report includes further information on any trends and it will certainly communicate all the data and the stats around the particular issue of blood clots. thank you. the particular issue of blood clots. thank you-— the particular issue of blood clots. thank ou. ., ., ., thank you. the thing i would add to what doctor— thank you. the thing i would add to what doctor raine _ thank you. the thing i would add to what doctor raine has _ thank you. the thing i would add to what doctor raine hasjust - thank you. the thing i would add to what doctor raine hasjust said - thank you. the thing i would add to what doctor raine hasjust said is l what doctor raine hasjust said is firstly— what doctor raine hasjust said is firstly all— what doctor raine hasjust said is firstly all of medicine is about saying — firstly all of medicine is about saying what other potential of the treatment? every drug you take, every— treatment? every drug you take, every vaccine, every operation will have _ every vaccine, every operation will have some — every vaccine, every operation will have some risks, often very small, including _ have some risks, often very small, including drugs people are very used to, like _ including drugs people are very used to, like aspirin. that can cause bleeding — to, like aspirin. that can cause bleeding and a whole variety of problems, and yet we all would see that as _ problems, and yet we all would see that as a _ problems, and yet we all would see that as a normal drug that people have _ that as a normal drug that people have in_ that as a normal drug that people have in their bathroom cabinet. all drugs _ have in their bathroom cabinet. all drugs have — have in their bathroom cabinet. all drugs have some side effects that are rare. — drugs have some side effects that are rare, the question is are the benefits— are rare, the question is are the benefits big enough tojustify are rare, the question is are the benefits big enough to justify that? what we _ benefits big enough to justify that? what we have here is an incredibly small— what we have here is an incredibly small potential risk, and even this is a potential risk and not one that is a potential risk and not one that is certain — is a potential risk and not one that is certain. so five people out of the it _ is certain. so five people out of the 11 million who have been given the 11 million who have been given the vaccine — the 11 million who have been given the vaccine in the uk so far, against _ the vaccine in the uk so far, against the really very substantial protection that these vaccines give and that— protection that these vaccines give and that the astrazeneca vaccine as well as— and that the astrazeneca vaccine as well as the — and that the astrazeneca vaccine as well as the pfizer vaccine given to protect _ well as the pfizer vaccine given to protect people against this really common— protect people against this really common disease. it is important to remind _ common disease. it is important to remind people that at this point in time we _ remind people that at this point in time we are still in a situation where — time we are still in a situation where the _ time we are still in a situation where the office for national statistics think that one in 270 people — statistics think that one in 270 people have got covid. this is still a common— people have got covid. this is still a common disease and it is a very dangerous— a common disease and it is a very dangerous disease for many people. people _ dangerous disease for many people. people dying and people getting significant blood clotting problems, that is— significant blood clotting problems, that is a _ significant blood clotting problems, that is a risk of covid, and people having _ that is a risk of covid, and people having long—term physical and mental effects— having long—term physical and mental effects from covid. it is a very significant _ effects from covid. it is a very significant disease, it is very common— significant disease, it is very common with very effective vaccines with astrazeneca and pfizer, and real issues — with astrazeneca and pfizer, and real issues we always have to think about— real issues we always have to think about with — real issues we always have to think about with all drugs, but they are so much — about with all drugs, but they are so much smaller than the benefits of getting _ so much smaller than the benefits of getting the vaccine. the risk benefit _ getting the vaccine. the risk benefit is _ getting the vaccine. the risk benefit is strongly in favour of getting — benefit is strongly in favour of getting vaccinated. as the european medicines— getting vaccinated. as the european medicines safety agency has also said, _ medicines safety agency has also said. it _ medicines safety agency has also said. it is — medicines safety agency has also said. it is a — medicines safety agency has also said, it is a universal view and it is also _ said, it is a universal view and it is also the — said, it is a universal view and it is also the view of the world health organization. is also the view of the world health organization-— is also the view of the world health oruanization. ., ., a, , ., organization. thanks, and barry asks in the liuht organization. thanks, and barry asks in the light of— organization. thanks, and barry asks in the light of the _ organization. thanks, and barry asks in the light of the european - in the light of the european president, the european commission president, the european commission president threatening to block the export of vaccines, how will this affect the general public you are waiting for the second dose of the pfizer vaccine which is produced in belgium? barry, thank you very much. i think people should be under no anxiety or misapprehensions about that, we will get on and deliver all the second doses of the pfizer vaccine. it is important to stress, whatever you may hear about the pressures that different countries are under to deliver vaccines for their public, these vaccines are a multinational effort, they are produced as a result of international cooperation, and i want to stress that we in the uk will continue to view it in that spirit. we do not have any bans on exporting staff and we will continue to cooperate with our european friends. let's go to fergus walsh of the bbc. ., ~ friends. let's go to fergus walsh of the sac. ., ~ , ., friends. let's go to fergus walsh of the sac. ., ~ _, ~ , the bbc. thank you, prime minister. is there a danger _ the bbc. thank you, prime minister. is there a danger that _ the bbc. thank you, prime minister. is there a danger that the _ the bbc. thank you, prime minister. j is there a danger that the unfounded concerns— is there a danger that the unfounded concerns about — is there a danger that the unfounded concerns about the _ is there a danger that the unfounded concerns about the safety _ is there a danger that the unfounded concerns about the safety of - is there a danger that the unfounded concerns about the safety of the - concerns about the safety of the astrazeneca _ concerns about the safety of the astrazeneca vaccine _ concerns about the safety of the astrazeneca vaccine might - concerns about the safety of the astrazeneca vaccine might put l concerns about the safety of the - astrazeneca vaccine might put some people _ astrazeneca vaccine might put some people off _ astrazeneca vaccine might put some people off from _ astrazeneca vaccine might put some people off from having _ astrazeneca vaccine might put some people off from having their- astrazeneca vaccine might put some people off from having theirjab? - people off from having theirjab? what _ people off from having theirjab? what would — people off from having theirjab? what would you _ people off from having theirjab? what would you say— people off from having theirjab? what would you say to _ people off from having theirjab? what would you say to them? . people off from having theirjab?| what would you say to them? for professor — what would you say to them? for professor chris _ what would you say to them? for professor chris whitty, _ what would you say to them? for professor chris whitty, how - professor chris whitty, how important _ professor chris whitty, how important is _ professor chris whitty, how important is it— professor chris whitty, how important is it that - professor chris whitty, how important is it that the - professor chris whitty, how. important is it that the under professor chris whitty, how - important is it that the under 505 -et important is it that the under 505 get immunised _ important is it that the under 505 get immunised a5 _ important is it that the under 505 get immunised as soon _ important is it that the under 505 get immunised as soon as- important is it that the under 505 i get immunised as soon as possible? thank— get immunised as soon as possible? thank you _ get immunised as soon as possible? thank you fergus, _ get immunised as soon as possible? thank you. fergus, the _ get immunised as soon as possible? thank you. fergus, the best- thank you. fergus, the best testimony that i can offer about the safety of the pfizer and the oxford astrazeneca, which seem to be pretty much identical in safety terms, is really what you have heard just now from doctor raine and professor whitty. | from doctor raine and professor whitty. i think they are medical professionals whose view it is that these are safe and effective vaccines. that has been confirmed today by the european medicines agency. i think that is a voice that will be heard around the whole of the european union and that is all to the good. i the european union and that is all to the good-— the european union and that is all to the good. i will add to that. the overwhelming _ to the good. i will add to that. the overwhelming professional - to the good. i will add to that. the overwhelming professional view i to the good. i will add to that. the overwhelming professional view of doctors _ overwhelming professional view of doctors around the world and other health— doctors around the world and other health professionals is these vaccines— health professionals is these vaccines are highly effective against _ vaccines are highly effective against a dangerous infection that is common, and they are safe, very safe, _ is common, and they are safe, very safe, relative — is common, and they are safe, very safe, relative to the risk of the infection _ safe, relative to the risk of the infection. there is a very strong professional consensus on that and it is clear— professional consensus on that and it is clear the british public also have _ it is clear the british public also have taken that message. if you look at the _ have taken that message. if you look at the numbers of people coming forward _ at the numbers of people coming forward for vaccination, well over 90%_ forward for vaccination, well over 90% in— forward for vaccination, well over 90% in the — forward for vaccination, well over 90% in the age groups that have gone through— 90% in the age groups that have gone through their vaccination have chosen— through their vaccination have chosen to _ through their vaccination have chosen to take this up. the general public— chosen to take this up. the general public is, _ chosen to take this up. the general public is, as— chosen to take this up. the general public is, as always, sensible and steady— public is, as always, sensible and steady on — public is, as always, sensible and steady on this. they understand this is a dangerous disease and it is an effective _ is a dangerous disease and it is an effective vaccine and has got very low side — effective vaccine and has got very low side effects compared to the risks— low side effects compared to the risks of— low side effects compared to the risks of catching the disease. in terms _ risks of catching the disease. in terms of— risks of catching the disease. in terms of the under 505, the biggest risk, as— terms of the under 505, the biggest risk, as everyone will by now know, is in mostly— risk, as everyone will by now know, is in mostly those who are older or who have — is in mostly those who are older or who have health conditions. it is quite _ who have health conditions. it is quite right— who have health conditions. it is quite right that they were prioritised. in terms of people who have sadly— prioritised. in terms of people who have sadly died from covid, 99% of people _ have sadly died from covid, 99% of people who died would have come from either— people who died would have come from either people over 50 or with pre—existing health conditions who are in— pre—existing health conditions who are in the — pre—existing health conditions who are in the group is currently being vaccinated — are in the group is currently being vaccinated. that was the absolute priority _ vaccinated. that was the absolute priority. we know a second vaccine on top _ priority. we know a second vaccine on top of _ priority. we know a second vaccine on top of the first adds to the protection. it is really important that people who are invited for a second _ that people who are invited for a second vaccination come and get it, in particular— second vaccination come and get it, in particular these people in the first groups over 50 and with health conditions — first groups over 50 and with health conditions. once they are vaccinated it is important that we go down the a-es it is important that we go down the ages because people can continue to have significant health problems in their 40s. — have significant health problems in theiraos, 305, have significant health problems in their 405, 305, 205 have significant health problems in theiraos, 305, 205 and have significant health problems in their 405, 305, 205 and occasionally even younger than that. but it decreases over age, but there are still significant health problems all the — still significant health problems all the way through. it will be critical— all the way through. it will be critical that once we have got through— critical that once we have got through the first group, of the ones most _ through the first group, of the ones most at _ through the first group, of the ones most at risk, that we go on to do this protection. it does one additional thing, which is the higher— additional thing, which is the higher the proportion of the population vaccinated, the smaller the risk— population vaccinated, the smaller the risk to— population vaccinated, the smaller the risk to everybody. by being vaccinated someone protects themselves and if they take the second — themselves and if they take the second vaccine, they protect themselves even more, but if they also have — themselves even more, but if they also have the vaccination they reduce — also have the vaccination they reduce the risk of passing on covid to people — reduce the risk of passing on covid to people around them. that is what we really _ to people around them. that is what we really want. they want to be vaccinated — we really want. they want to be vaccinated for their own protection and if— vaccinated for their own protection and if everyone is protected, it protects — and if everyone is protected, it protects everyone else in society. emily— protects everyone else in society. emily morgan, itv. you protects everyone else in society. emily morgan, itv.— protects everyone else in society. emily morgan, itv. you said there is no chance emily morgan, itv. you said there is no change to — emily morgan, itv. you said there is no change to the _ emily morgan, itv. you said there is no change to the road _ emily morgan, itv. you said there is no change to the road map, - emily morgan, itv. you said there is no change to the road map, but - emily morgan, itv. you said there is no change to the road map, but you| no change to the road map, but you have also _ no change to the road map, but you have also said — no change to the road map, but you have also said in _ no change to the road map, but you have also said in the _ no change to the road map, but you have also said in the past _ no change to the road map, but you have also said in the past we - no change to the road map, but you have also said in the past we will i have also said in the past we will only move — have also said in the past we will only move to— have also said in the past we will only move to the _ have also said in the past we will only move to the next _ have also said in the past we will only move to the next phase - have also said in the past we will only move to the next phase of. only move to the next phase of easing — only move to the next phase of easing of— only move to the next phase of easing of lockdown _ only move to the next phase of easing of lockdown if— only move to the next phase of easing of lockdown if we - only move to the next phase ofi easing of lockdown if we passed only move to the next phase of- easing of lockdown if we passed four tests _ easing of lockdown if we passed four tests doesn't— easing of lockdown if we passed four tests. doesn't this _ easing of lockdown if we passed four tests. doesn't this vaccine _ easing of lockdown if we passed four tests. doesn't this vaccine supply . tests. doesn't this vaccine supply issue _ tests. doesn't this vaccine supply issue mean— tests. doesn't this vaccine supply issue mean that _ tests. doesn't this vaccine supply issue mean that we _ tests. doesn't this vaccine supply issue mean that we are _ tests. doesn't this vaccine supply issue mean that we are actually. issue mean that we are actually going _ issue mean that we are actually going to — issue mean that we are actually going to fail _ issue mean that we are actually going to fail the _ issue mean that we are actually going to fail the first _ issue mean that we are actually going to fail the first test, - issue mean that we are actuallyl going to fail the first test, which is the _ going to fail the first test, which is the continued _ going to fail the first test, which is the continued successful- is the continued successful deployment— is the continued successful deployment of— is the continued successful deployment of the - is the continued successfull deployment of the vaccine? no, is the short answer to that, we will be able to meet our targets in exactly the way that i described, by the 12th of april, and byjuly, and thatis the 12th of april, and byjuly, and that is the crucial thing, and that will enable us to get on with the steps on the timetable that we have set out, so, the 12th of april, the 17th of may, the 21st ofjune, we will continue all the unlockings that i have set out, if the four tests, as i have said, continue to be met. thank you very much. tom newton dunn, times radio.- be met. thank you very much. tom newton dunn, times radio. thank you, prime minister. _ newton dunn, times radio. thank you, prime minister. a _ newton dunn, times radio. thank you, prime minister. a question _ newton dunn, times radio. thank you, prime minister. a question for- prime minister. a question for professor whitty. our vaccine centres, gps, whoever, banned from administering vaccines to under 505, if they have stock left over, if they have done all the others? and a question to you, prime minister, on the role of india in stopping the institute from exporting for million doses, which you havejust institute from exporting for million doses, which you have just said they have done, what was the indian government's role in that, do you know, and furthermore, if they have indeed stopped the institute from exporting, is that not the same vaccine nationalism that has been allegedly affecting the eu and india? ,, allegedly affecting the eu and india? . ., , allegedly affecting the eu and india? ,, ., , , allegedly affecting the eu and india? ,, .,, , ., , allegedly affecting the eu and india? ,, , ., ,~ ., india? the nhs has been really clear that what they _ india? the nhs has been really clear that what they want _ india? the nhs has been really clear that what they want to _ india? the nhs has been really clear that what they want to do _ india? the nhs has been really clear that what they want to do is - india? the nhs has been really clear that what they want to do is to - that what they want to do is to prioritise — that what they want to do is to prioritise those in the over—505 and the high—risk groups plus health and social— the high—risk groups plus health and social care _ the high—risk groups plus health and social care workers. and carers of vulnerable — social care workers. and carers of vulnerable people. and they have done _ vulnerable people. and they have done that — vulnerable people. and they have done that for a really obvious reason — done that for a really obvious reason, which i think everybody accepts — reason, which i think everybody accepts. what there is leading this have said. — accepts. what there is leading this have said, and i completely agree with this, — have said, and i completely agree with this, is— have said, and i completely agree with this, is that we must at this point _ with this, is that we must at this point really _ with this, is that we must at this point really prioritise the possibility that we don't miss anybody, leave anybody behind, because — anybody, leave anybody behind, because we are racing down the ages. just to— because we are racing down the ages. just to give _ because we are racing down the ages. just to give something, the society of actuaries gave some numbers on this to _ of actuaries gave some numbers on this to explain why this is so important, and what they said was that if— important, and what they said was that if we — important, and what they said was that if we assume the vaccine is completely effective, which it isn't, — completely effective, which it isn't, but _ completely effective, which it isn't, but very, very close to that, for practical — isn't, but very, very close to that, for practical purposes, you would need _ for practical purposes, you would need to— for practical purposes, you would need to vaccinate 20 people in the highest _ need to vaccinate 20 people in the highest risk group to actually prevent— highest risk group to actually prevent one death. by the time you -et prevent one death. by the time you get down _ prevent one death. by the time you get down to the people in their 505, who are _ get down to the people in their 505, who are otherwise well, don't have other— who are otherwise well, don't have other problems, you would need to vaccinate _ other problems, you would need to vaccinate 8000 people to prevent one death _ vaccinate 8000 people to prevent one death the _ vaccinate 8000 people to prevent one death. the point i am making is, the key priority— death. the point i am making is, the key priority at the moment is to find all— key priority at the moment is to find all the people who've not yet had the _ find all the people who've not yet had the opportunity to be offered a vaccine _ had the opportunity to be offered a vaccine in — had the opportunity to be offered a vaccine in the highest risk groups, complete — vaccine in the highest risk groups, complete on that, and then we absolutely want to go further down the ages — absolutely want to go further down the ages. but that is the reason for these _ the ages. but that is the reason for these decisions.— these decisions. yes, and tom, on our these decisions. yes, and tom, on your question _ these decisions. yes, and tom, on your question about _ these decisions. yes, and tom, on your question about the _ these decisions. yes, and tom, on your question about the serum - your question about the serum institute of india, i want to thank the serum institute of india for their heroic role in producing huge quantities of vaccine, and the indian government hasn't stopped any export, there is a delay, as i have described, as there is very frequently in vaccine roll—out programs, but this is believe me by no means the end of the story of the uk's relationship with the serum institute of india, and we hope to make further progress over the weeks and months ahead. there is a huge amount of work that we want to do together, and this isjust amount of work that we want to do together, and this is just the beginning. thanks very much, tom. i think you wanted to come back on something. do you want to come back? very quickly, yeah. of the indian government delayed that export? ida. government delayed that export? no, no. there government delayed that export? no, no- there is — government delayed that export? no, no- there is a — government delayed that export? no, no. there is a delay, as there often is, for various technical reasons, but we hope, as i have said, to continue to work very closely with the serum institute of india, and indeed with partners around the world, including on the european continent. so, this is a big international effort, and we are going to continue as the uk to be global in our outlook, as you would expect us to be. global in our outlook, as you would expect us to be— global in our outlook, as you would expect us to be. prime minister, you have previously _ expect us to be. prime minister, you have previously called _ expect us to be. prime minister, you have previously called for _ expect us to be. prime minister, you have previously called for an - have previously called for an amnesty _ have previously called for an amnesty for migrants who are in the uk illegally, how comfortable are you with — uk illegally, how comfortable are you with the idea of sending asylum seekers— you with the idea of sending asylum seekers overseas for processing? and professor— seekers overseas for processing? and professor whitty, the latest figures suggest _ professor whitty, the latest figures suggest thatjust one professor whitty, the latest figures suggest that just one in professor whitty, the latest figures suggest thatjust one in 16,000 tests— suggest thatjust one in 16,000 tests on— suggest thatjust one in 16,000 tests on schoolchildren have come back positive. how positive are you that we _ back positive. how positive are you that we will— back positive. how positive are you that we will be able to proceed with the easing — that we will be able to proceed with the easing of the lockdown on the 12th of— the easing of the lockdown on the 12th of april?— 12th of april? steve, the first oint 12th of april? steve, the first point about _ 12th of april? steve, the first point about the _ 12th of april? steve, the first point about the illegal - 12th of april? steve, the first - point about the illegal immigration into the uk is that, and you are perfectly right, when people have been here for a very long time and haven't fallen foul of the law, then it makes sense to try to regularise their status, it makes sense to try to regularise theirstatus, but it makes sense to try to regularise their status, but that actually is pretty much what already happens under the existing rules. but when it comes to what the home secretary was setting out, i want to be clear, the objective here is to save life and avert human misery, because people are crossing thejeane freeman, who are being fooled, who are being conned, by gangsters into paying huge sums of money. —— crossing the channel —— and it is a deeply repugnant traffic, people have died, which we need to stop. and that is why we have set out a tough series of proposals that you have seen. but the objective is a humanitarian one, and a humane one, which is to stop the abuse of these people buy a bunch of traffickers and gangsters. that is what we're trying to do. fin and gangsters. that is what we're trying to do-_ trying to do. on schools, three oints to trying to do. on schools, three points to make, _ trying to do. on schools, three points to make, the _ trying to do. on schools, three points to make, the first - trying to do. on schools, three points to make, the first of - trying to do. on schools, three i points to make, the first of which is a huge — points to make, the first of which is a huge thank you to teachers and other— is a huge thank you to teachers and other school staff, who have done really _ other school staff, who have done really terrific work in making it as safe as _ really terrific work in making it as safe as possible for all children to come _ safe as possible for all children to come back, and remembering of course that children _ come back, and remembering of course that children are not the group who are heavily— that children are not the group who are heavily affected by this infection. but they are important potentially in the transmission. and what they— potentially in the transmission. and what they are doing in the schools is really _ what they are doing in the schools is really going to benefit students, staff and _ is really going to benefit students, staff and wider society. in terms ofm _ staff and wider society. in terms ofm we — staff and wider society. in terms ofm we are _ staff and wider society. in terms of... we are expecting that schools going _ of... we are expecting that schools going back— of... we are expecting that schools going back will put some upward pressure — going back will put some upward pressure on the r—rate, we have said that from _ pressure on the r—rate, we have said that from beginning, that was an accepted — that from beginning, that was an accepted thing that was likely to happen — accepted thing that was likely to happen, but the roadmap was planned with that _ happen, but the roadmap was planned with that possibility absolutely in mind, _ with that possibility absolutely in mind, when the prime minister announced _ mind, when the prime minister announced it. and what he also said, and this— announced it. and what he also said, and this is— announced it. and what he also said, and this isjust reiterating what he said, _ and this isjust reiterating what he said. was— and this isjust reiterating what he said, was that he and ministers want everything _ said, was that he and ministers want everything to be based on data, not dates _ everything to be based on data, not dates and — everything to be based on data, not dates. and we have not yet got to the point — dates. and we have not yet got to the point where we can see the full impact _ the point where we can see the full impact of— the point where we can see the full impact of schools being open again, and therefore what we will need to do is _ and therefore what we will need to do is to— and therefore what we will need to do is to look again at the data, once _ do is to look again at the data, once it — do is to look again at the data, once it comes in. but it takes awhile — once it comes in. but it takes awhile for— once it comes in. but it takes awhile for the data fully to reveal itself _ awhile for the data fully to reveal itself and — awhile for the data fully to reveal itself and to be properly analysed in the _ itself and to be properly analysed in the way that the prime minister and other— in the way that the prime minister and other ministers can make a decision — and other ministers can make a decision. so it is important that we stick— decision. so it is important that we stick to— decision. so it is important that we stick to this — decision. so it is important that we stick to this data, not dates, approach _ stick to this data, not dates, approach. but there is nothing at the moment that is flashing red lights, — the moment that is flashing red lights, beyond what what we would expect, _ lights, beyond what what we would expect, which is of course when the schools _ expect, which is of course when the schools open, there is a slightly greater— schools open, there is a slightly greater possible at the transmission. we willjust have to see what— transmission. we willjust have to see what the data shows. | transmission. we willjust have to see what the data shows. i will 'ust sa , see what the data shows. i will 'ust say. steve. — see what the data shows. i will 'ust say. steve. on fl see what the data shows. i will 'ust say, steve, on schools, * see what the data shows. i will 'ust say, steve, on schools, i�* see what the data shows. i will 'ust say, steve, on schools, i wash see what the data shows. i willjust say, steve, on schools, i was at. see what the data shows. i willjust say, steve, on schools, i was at a i say, steve, on schools, i was at a primary school in my constituency today, and the feeling, they were glad to be back, it was obvious, all the pupils said, and i want to echo what chris said, i want to thank all of the teachers who have done an amazing amount of work getting their schools ready, all the parents who put up with lockdown for so long and worked so hard, and i think i am right in saying that the attendance todayis right in saying that the attendance today is actually higher than we would normally expect it to be at this time of year. and it was very, very good to see the enthusiast for being back at school and the steps that schools are still taking, rightly so, to ensure that it is covid—secure. rightly so, to ensure that it is covid-secure.— rightly so, to ensure that it is covid-secure. thank you, prime minister. covid-secure. thank you, prime minister- if _ covid-secure. thank you, prime minister. if i — covid-secure. thank you, prime minister. ifi can _ covid-secure. thank you, prime minister. if i can ask _ covid-secure. thank you, prime minister. if i can ask professor i minister. if i can ask professor whitty, have you seen any evidence that the suspension of the oxford vaccine in some european countries has had any impact here in terms of people not turning up for appointments or perhaps asking for an alternative? and prime minister, next week is the anniversary of the start of the first lockdown, i think you have said that you will privately observe a minute's silence, as the merry chiriches to has asked people to do, should we see it as a national day of commemoration for those that we've lost in this pandemic, and have you given any more thought to a permanent memorial to them? fin given any more thought to a permanent memorial to them? on the auestion permanent memorial to them? on the question that — permanent memorial to them? on the question that you _ permanent memorial to them? on the question that you asked _ permanent memorial to them? on the question that you asked me, - permanent memorial to them? on the question that you asked me, there - question that you asked me, there are anecdotal reports which i am sure _ are anecdotal reports which i am sure will— are anecdotal reports which i am sure will be accurate that in some places. _ sure will be accurate that in some places. a — sure will be accurate that in some places, a few people have not turned up places, a few people have not turned up immediately after they heard the news _ up immediately after they heard the news i_ up immediately after they heard the news. i suspect a lot of them will think— news. i suspect a lot of them will think about — news. i suspect a lot of them will think about it, see the very reassuring data that the mhra has given _ reassuring data that the mhra has given, laid out by drjune raine earlier, — given, laid out by drjune raine earlier, the very reassuring points made _ earlier, the very reassuring points made the — earlier, the very reassuring points made the who, the very issue reassuring things are said by the european — reassuring things are said by the european medicines agency, and the overwhelming view of the health professions, and they will realise that this — professions, and they will realise that this is — professions, and they will realise that this is something which, having had a _ that this is something which, having had a pause — that this is something which, having had a pause for thought, they want to do _ had a pause for thought, they want to do but — had a pause for thought, they want to do. but the numbers were very small. _ to do. but the numbers were very small. who — to do. but the numbers were very small, who did that. actually, almost — small, who did that. actually, almost record numbers have been going _ almost record numbers have been going through in terms of numbers of people _ going through in terms of numbers of people taking up the vaccine. overall. _ people taking up the vaccine. overall, there is no evidence of a significant — overall, there is no evidence of a significant problem that people do not want _ significant problem that people do not want vaccination. and anyone who is doubtful— not want vaccination. and anyone who is doubtful about this, i would encourage them to think through the dangers— encourage them to think through the dangers of— encourage them to think through the dangers of covid, how common it is, and the _ dangers of covid, how common it is, and the safety of the vaccines. this is something which absolutely is in their interests, as well as in the interests — their interests, as well as in the interests of everyone around them, for them _ interests of everyone around them, for them to— interests of everyone around them, for them to take. and interests of everyone around them, for them to take.— for them to take. and on the anniversary. _ for them to take. and on the anniversary, of— for them to take. and on the anniversary, of course - for them to take. and on the anniversary, of course i - for them to take. and on the anniversary, of course i will. for them to take. and on the i anniversary, of course i will be marking it, as i am sure millions of others will around the country. and on the idea for a national memorial, yes, we will certainly be pursuing that, and a lot of good suggestions have already come in, you will be hearing more about that in due course. ,., ., ., hearing more about that in due course. ., i. course. good evening. for you, prime minister, course. good evening. for you, prime minister. when _ course. good evening. for you, prime minister, when will _ course. good evening. for you, prime minister, when will cross-border - minister, when will cross—border travel— minister, when will cross—border travel be — minister, when will cross—border travel be relaxed _ minister, when will cross—border travel be relaxed enough- minister, when will cross—border travel be relaxed enough for- minister, when will cross—border travel be relaxed enough for the| travel be relaxed enough for the 800.000 — travel be relaxed enough for the 800,000 scots— travel be relaxed enough for the 800,000 scots in— travel be relaxed enough for the 800,000 scots in england - travel be relaxed enough for the 800,000 scots in england to. travel be relaxed enough for thej 800,000 scots in england to be travel be relaxed enough for the - 800,000 scots in england to be able to -o 800,000 scots in england to be able to go home _ 800,000 scots in england to be able to go home and — 800,000 scots in england to be able to go home and see _ 800,000 scots in england to be able to go home and see their— 800,000 scots in england to be able to go home and see their families? i to go home and see their families? secondly, — to go home and see their families? secondly do— to go home and see their families? secondly do you _ to go home and see their families? secondly, do you think _ to go home and see their families? secondly, do you think nicola - secondly, do you think nicola sturgeon _ secondly, do you think nicola sturgeon should _ secondly, do you think nicola sturgeon should resign - secondly, do you think nicola sturgeon should resign if- secondly, do you think nicola sturgeon should resign if she| secondly, do you think nicola - sturgeon should resign if she broke the ministerial— sturgeon should resign if she broke the ministerial code, _ sturgeon should resign if she broke the ministerial code, and _ sturgeon should resign if she broke the ministerial code, and would - sturgeon should resign if she broke| the ministerial code, and would you expect— the ministerial code, and would you expect the — the ministerial code, and would you expect the same _ the ministerial code, and would you expect the same of— the ministerial code, and would you expect the same of your _ the ministerial code, and would you expect the same of your own - expect the same of your own ministers? _ expect the same of your own ministers?— expect the same of your own ministers? ~ �* ., , , ministers? well, alex, hope very much that _ ministers? well, alex, hope very much that we _ ministers? well, alex, hope very much that we will _ ministers? well, alex, hope very much that we will be _ ministers? well, alex, hope very much that we will be able - ministers? well, alex, hope very much that we will be able to - ministers? well, alex, hope veryl much that we will be able to move around as one united kingdom, according to the timetable set out on the roadmap, and i hope that everybody will show common sense in application of the rules around the country. as i have said earlier on, there is no change to the roadmap as a result of anything to do with the vaccine roll—out, which continues well, and i think your second question was an attempt to get me, quite properly, to get me to comment on something which i think is properly and rightly left to parliament in scotland to address and to the scottish electorate. ok, everybody, thank you very much. so, the prime minister bringing to a close his latest coronavirus briefing, alongside the england chief medical officer chris whitty, and drjune raine from the medicines rule later agency. very important that dr raine was there because the tenor of the news conference was that the astrazeneca vaccine is safe, and that has been reiterated of course by the european medicines agency as well. and crucially, for many people watching this broadcast, i suspect, the prime minister made it clear that as far as he is concerned, despite those logjams perhaps and supply problems concerning vaccines coming particularly from india, the timetable for the unlocking of coronavirus restrictions remains in place. that roadmap will not be affected by the suggestion is that we have just had. let's affected by the suggestion is that we havejust had. let'sjust affected by the suggestion is that we have just had. let's just remind ourselves of some of the key points made by the prime minister in that briefing today. on the continuing discussion over the safety of the oxford astrazeneca vaccine, the prime minister reiterated the point that the benefits of it preventing covid far outweigh any risks, as confirmed by the uk medicines rule eight to be bored. he confirmed that he himself will be getting the astrazeneca job tomorrow. i will, too. drjune raine... ijust thought i would throw that in! drjune raine, of the medicines regulator, said the scientific review shows there is no difference in the number of blood clots appearing in people who have had the jab, compared to those who have not. several countries had suspended the astrazeneca vaccine over blood clot fears. the prime minister said he did not expect a reduction in supply to impact, as i have said, the timetable for easing coronavirus restrictions. the vaccine programme is still on track as per the targets set out by the government. we can get some expert analysis now, with nick triggle, our health correspondent. yes, he's pointing up the fact that the uk regulator says astrazeneca is fine, the european regulator says astrazeneca is fine, and as a result, no change in the timetable, the roadmap to unlocking the country?— the country? indeed, the road map was set out — the country? indeed, the road map was set out on _ the country? indeed, the road map was set out on the _ the country? indeed, the road map was set out on the premise - the country? indeed, the road map was set out on the premise that. the country? indeed, the road map| was set out on the premise that the vaccination — was set out on the premise that the vaccination programme _ was set out on the premise that the vaccination programme would - was set out on the premise that the i vaccination programme would continue and the _ vaccination programme would continue and the key— vaccination programme would continue and the key targets— vaccination programme would continue and the key targets were _ vaccination programme would continue and the key targets were mid - vaccination programme would continue and the key targets were mid april- and the key targets were mid april for all— and the key targets were mid april for all over— and the key targets were mid april for all over 505— and the key targets were mid april for all over 505 to _ and the key targets were mid april for all over 505 to be _ and the key targets were mid april for all over 505 to be offered - and the key targets were mid april for all over 505 to be offered their| for all over 505 to be offered their first dose — for all over 505 to be offered their first dose of— for all over 505 to be offered their first dose of vaccination, - for all over 505 to be offered their first dose of vaccination, and - for all over 505 to be offered their first dose of vaccination, and then all adults— first dose of vaccination, and then all adults to — first dose of vaccination, and then all adults to be _ first dose of vaccination, and then all adults to be offered _ first dose of vaccination, and then all adults to be offered a - first dose of vaccination, and then all adults to be offered a first - all adults to be offered a first dose — all adults to be offered a first dose by— all adults to be offered a first dose by the _ all adults to be offered a first dose by the end _ all adults to be offered a first dose by the end of— all adults to be offered a first dose by the end ofjuly. - all adults to be offered a first dose by the end ofjuly. what the government _ dose by the end ofjuly. what the government had _ dose by the end ofjuly. what the government had hoped _ dose by the end ofjuly. what the government had hoped was - dose by the end ofjuly. what the government had hoped was they| dose by the end ofjuly. what the - government had hoped was they could do this even more rapidly. they would get extra doses in from india and be able to rapidly go through these age groups. there was a briefing last week that this would happen. they have had to row back on that because of the problems in getting some of the stocks from india, half the 10 million that had been ordered have turned up, so 5 million yet to arrive. but that should not, the government say, interfere with the lifting of restrictions. what we do need as we get into april is those stocks from india to arrive and perhaps more doses of a third vaccine made by moderna, approved for use in the uk. we may start getting doses of that in, so we will need more vaccine. we cannot take this as a given, the supply chains are fragile and we have been reminded of how fragile the supply chain is. but have been reminded of how fragile the supply chain is.— the supply chain is. but any shortfall — the supply chain is. but any shortfall could _ the supply chain is. but any shortfall could potentially l the supply chain is. but anyl shortfall could potentially be the supply chain is. but any - shortfall could potentially be made up shortfall could potentially be made up by the moderna vaccine? fate shortfall could potentially be made up by the moderna vaccine? we have ordered 17 million _ up by the moderna vaccine? we have ordered 17 million doses _ up by the moderna vaccine? we have ordered 17 million doses of _ up by the moderna vaccine? we have ordered 17 million doses of that - up by the moderna vaccine? we have ordered 17 million doses of that and i ordered 17 million doses of that and we will not get that in one big tranche. we will get a few million in april. i think the suppliers from india will be important, if we get those in. we have got two astrazeneca plans in the uk that produce around 2 million doses a week. the pfizer stocks, from belgium. we get around 1 million a week from the belgian plans. if we can increase those, that will help. lots of things still need to go right, but the government is confident it can still achieve those targets and the restrictions can still lift. , ., ., , still lift. interesting that italy has already — still lift. interesting that italy has already announced - still lift. interesting that italy has already announced it - still lift. interesting that italy has already announced it will| still lift. interesting that italy - has already announced it will resume using the astrazeneca vaccine as a result of that ruling from the european medicines agency. i expect we will hear — european medicines agency. i expect we will hear other _ european medicines agency. i expect we will hear other countries - european medicines agency. i expect we will hear other countries are - we will hear other countries are making the same decision. the european regulator was very clear that the benefits far outweigh any possible risks will stop they have identified 18 cases of this rare blood clot in the brain. but that is out of 20 million astrazeneca vaccinations being given. for every 1 million vaccinations, one case of this rare blood clot. to put that into perspective, for the over 75 is affected with covid, they have got a one in nine chance of dying. even amongst younger age groups the risk—benefit ratio is very clear. people in their aos, if they are infected with covid, they have a one infected with covid, they have a one in 1000 chance of dying. this has not been proved yet, but if a link is proved between the vaccine and the rare blood clot, the benefits of vaccination would far outweigh any risks. . .. . , vaccination would far outweigh any risks. ., , ., the latest coronavirus figures from the government show there were 5,758 positive cases reported in the last 2a hour period, that's compared to 6,752 last week. a further 1a1 people died within 28 days of a positive test, down from 181 deaths reported last thursday. and a62,2a6 people received a first dose of a coronavirus vaccine. let's get more from damian grammaticas at westminster. sorry, i cut you off to hear the prime minister a bit earlier on. cut you off to hear the prime ministera bit earlier on. ijust wanted to know how the government is messaging handling the suggestion that perhaps they might not be able to meet their targets for the vaccination programme, given the hiccup to supplies from places like india? it hiccup to supplies from places like india? . . ~ . india? it was the prime minister cominu india? it was the prime minister comin: to india? it was the prime minister coming to the — india? it was the prime minister coming to the podium, - india? it was the prime minister coming to the podium, so - india? it was the prime minister coming to the podium, so it - india? it was the prime ministerj coming to the podium, so it was india? it was the prime minister- coming to the podium, so it was what we were all waiting for. what they were doing was very clear. you heard several things. were doing was very clear. you heard severalthings. number were doing was very clear. you heard several things. number one was this repeated message about the safety of the astrazeneca vaccine. and they wanted to repeat that, repeat the mhra here, you heard from june rain in the briefing saying they are happy the vaccine is safe, the europeans are, the world health organization. that is dealing with one thing. dealing with the roll—out, again a very clear message, borisjohnson saying they would continue to give second doses evenif would continue to give second doses even if there is going to be a drop in the supplies compared to what they expected. the roll—out is still progressing and broadly the targets looking ahead will be met. that is the second message. allied to that, the second message. allied to that, the message borisjohnson was saying was the unlocking of the restrictions, he expects those will still be on track as well. he does not see any change to that. he was wanting to line up all of those things and say that despite the shortfalls in vaccine deliveries, compared to what they had been planning for, they do not think there will be any impact. interestingly he was asked have there been reports that the indian government may have been wanting to keep vaccines for its own use and witty comment on that? would he call this vaccine nationalism when he criticised european countries or the european union? borisjohnson did not go there at all. he said he wanted to thank india for their heroic efforts, the serum institute of india, which produces those vaccines. . . . of india, which produces those vaccines. , , . ., ., ., vaccines. the public wanted to hear the prime minister _ vaccines. the public wanted to hear the prime minister and _ vaccines. the public wanted to hear the prime minister and they - vaccines. the public wanted to hearj the prime minister and they wanted to hear what he said about the road map for unlocking, which is on everyone's mines at the moment. he was adamant that despite the supply problems, that road map has not been affected. can he be that confident? it was interesting, wasn't it? he is definitely being confident. he said we will get on with the steps in the timetable laid out, all the unlockings, so all of those steps. but there was an interesting moment, i thought, which was chris whitty, the chief medical officer towards the chief medical officer towards the end in answering one of the questions, he was asked about some signs from tests being done now that schools have gone back in england, signs about the infection rates of covid amongst schoolchildren. he said it was too early to tell, there needed to be time to see the data properly, bat, and this was a message for the prime minister i think, we have to stick to this idea it is about data and not about dates. that seemed to be him picking up dates. that seemed to be him picking up on that point and saying we have to see the numbers. bud up on that point and saying we have to see the numbers.— to see the numbers. and with the su -l to to see the numbers. and with the supply to the _ to see the numbers. and with the supply to the road _ to see the numbers. and with the supply to the road map _ to see the numbers. and with the supply to the road map it - to see the numbers. and with the supply to the road map it could i to see the numbers. and with the | supply to the road map it could be something completely different. damian grammaticas in westminster. a review has concluded the oxford astrazeneca vaccine is safe. it follows the suspension of the jar by several european nations. earlier today the committee said it would continue to study links between rare blood clots and the vaccine. fiur blood clots and the vaccine. our exert blood clots and the vaccine. oi" expert committee on the safety of medicines has now come to a conclusion on the review of cases of blood clots in people vaccinated with astrazeneca's covid—19 vaccine. the committee has come to a clear scientific conclusion. this is a safe and effective vaccine. it's benefits in protecting people from covid-19 with the benefits in protecting people from covid—19 with the associated risks of death and hospitalisation outweigh the possible risks. the committee also concluded that the vaccine is not associated with an increase in the overall risk of thromboembolic events or blood clots. now, during the investigation and review we began to see a small number of cases of rare and unusual, but very serious, clotting disorders, and this triggered a more focused review. based on the evidence available and after days of in—depth analysis of lab results, clinical reports, autopsy reports and further information from the clinical trials we still cannot rule out definitively a link between these cases and the vaccine. what these cases and the vaccine. what the committee has therefore recommended is to raise awareness of these possible risks, making sure they are included in the product information, drawing attention to these possible rare conditions and providing information to health care professionals and vaccinated people will help to spot and mitigate any possible side—effects. we are also launching additional investigations to understand more about these rare cases and we are conducting targeted observational studies. about 7 million people have now been vaccinated in the eu with astrazeneca vaccine and 11 million have been vaccinated in the uk, and there is increasing use of this vaccine in other countries. it remains very important that all side effects are closely monitored and reported so that we can evaluate them and see if there is any need to update the information and warnings about possible risks. doctor strauss will explain the committee's evaluation in more detail, but i want to reiterate that our scientific position is that this vaccine is a safe and effective option to protect citizens against covid-19. it option to protect citizens against covid—19. it demonstrated that at least 60% efficacy in clinical trials in preventing coronavirus disease and the real world evidence suggests the effectiveness could be even higher than that. we are very much aware that some member states have paused vaccinations, waiting for the outcome of the review, but given that thousands of people in the eu die every day and in fact over 2500 were reported one day last week, it is really crucial for the ema to review rapidly and thoroughly all the available evidence. the european _ all the available evidence. the european medicines agency. we can get more reaction now from shadow health secretary, jonathan ashworth. thank you for being with us. the point the prime minister made a few minutes ago, that although there is an issue with suppliers, particularly from india at the moment, and various other issues as well, it does not seem to be the case that the road map for unlocking, for a lifting coronavirus restrictions, will be affected. are as he is quite we hope it is not affected, but that road map always has to be driven by the data, not just the dates. it has to be driven by the data, not just the dates.— has to be driven by the data, not just the dates. we re were hearing from i were hearing from the jvc eye we were hearing from the jvc eye earlier today that if the vaccination roll—out is now slower and those in their aos will not get their vaccination as quickly as we were anticipating a few days ago, there may well be more infection and there may well be more infection and the virus will continue to circulate. it is why we have always got to proceed with caution, we have always got to be driven by the data, we have got to assess all the steps taken in this road map. i mean, i like everybody wants to get out of lockdown, but we have got to do it in a safe way. the lockdown, but we have got to do it in a safe way-— in a safe way. the european medicines — in a safe way. the european medicines agency _ in a safe way. the european medicines agency made - in a safe way. the european medicines agency made it i in a safe way. the european i medicines agency made it clear in a safe way. the european - medicines agency made it clear that it cannot definitively at the moment say there is not a causal link between the blood clots and the astrazeneca vaccine, but the risks, the benefits of the vaccine far outweigh the risks. they are putting outweigh the risks. they are putting out an advisory, a warning to medical practitioners in europe about the astrazeneca vaccine. do you think that warning and advisory should be here in the uk as well? vaccination saves lives and whether it is the pfizer vaccine, the astrazeneca vaccine, or the moderna vaccine, which we anticipate coming online in a few weeks' time, please take this vaccination if you are offered it. it saves lives, it protects you, it protects others and we think it cuts transmission as well from the data. if you want to get out of this horrendous lockdown, if you want to get away from the situation where huge numbers of people have lost their lives, here in the uk we have got one of the highest death rates in the world tragically because of some of the mistakes that have been made in the last 12 months, please take the vaccination. it is safe, it is safe. obviously the prime minister has been saying that today, chris whitty has been saying that today and i as the labour spokesperson want to underline this point, vaccination saves lives, please take it up when offered. ., saves lives, please take it up when offered. ._ , saves lives, please take it up when offered. , , .,, ., offered. there may be people who will sa , offered. there may be people who will say. look. _ offered. there may be people who will say. look. i— offered. there may be people who will say, look, iwould _ offered. there may be people who will say, look, i would rather- offered. there may be people who will say, look, i would rather not i will say, look, iwould rather not have the astrazeneca, i would rather have the astrazeneca, i would rather have one of the other ones. moderna has been given licence to be used in this country now. millions of vials of that will be coming as well. the best vaccine _ of that will be coming as well. the best vaccine is _ of that will be coming as well. tis: best vaccine is the one that is in your arm. all these vaccinations protect you, they will protect your family, your neighbours, and it could save your life. that is what vaccination does, it saves lives. look, i know that stuff circulate online, it circulate by whatsapp, i see it. i am sat here in leicester where i live and i see all kind of misinformation shared, but at the end of the day having a vaccine is far better than you catching this oval virus and ending up in hospital with a machine, with pipes down your lungs to give the oxidant. vaccination saves lives, so please take it. there is no political difference here between the labour party and boris johnson. difference here between the labour party and borisjohnson. we all agree that vaccines are key to saving lives and getting out of this lockdown and i want to really emphasise this point and show the country that people are coming together to promote vaccination. do you think the indian government is engaging in vaccine nationalism? well, the prime minister told us tonight that the indian government isn't playing that game, and the prime minister will have presumably been speaking to people in the indian government on behalf of the united kingdom. but indian government on behalf of the united kingdom.— united kingdom. but what do you think? well, _ united kingdom. but what do you think? well, we _ united kingdom. but what do you think? well, we have _ united kingdom. but what do you think? well, we have to - united kingdom. but what do you think? well, we have to take - united kingdom. but what do you i think? well, we have to take the... if this is what _ think? well, we have to take the... if this is what the _ think? well, we have to take the... if this is what the prime _ think? well, we have to take the... if this is what the prime minister i if this is what the prime minister is telling us, then i think that is reasonable for us to take that at face value. but what we now need is to ensure that our government is doing all it can to resolve these issues with supply. the health secretary today, matt hancock, promised us, he gave us a cast—iron guarantee, that there was waiting for their second jobs throughout april will get that. we need to continue to get those reassurances from government. —— jabs. and then we need reassurances that once we get through april, the vaccinations will ramp up again, so those in their aos will ramp up again, so those in theiraos and will ramp up again, so those in their a05 and people like police officers will start getting those life—saving jabs as well. but officers will start getting those life-saving jabs as well.- officers will start getting those life-saving jabs as well. life-saving “abs as well. but it is clear that life-saving jabs as well. but it is clear that part _ life-saving jabs as well. but it is clear that part of _ life-saving jabs as well. but it is clear that part of the _ life-saving jabs as well. but it is clear that part of the reason - life-saving jabs as well. but it is clear that part of the reason we | life-saving jabs as well. but it is i clear that part of the reason we are experiencing a cut in supply in the uk is because of a rise in infections in india, and some of the stuff that they said was going to be coming to the uk, some of the vaccine, is not coming, as a result of that, that is vaccine nationalism, isn't it? ., , nationalism, isn't it? some of this is also to do _ nationalism, isn't it? some of this is also to do with, _ nationalism, isn't it? some of this is also to do with, as _ nationalism, isn't it? some of this is also to do with, as we _ nationalism, isn't it? some of this i is also to do with, as we understand it, from checking processes of the vaccination batches in india. so we need to make sure that the manufacturing processes and the checking processes are carried out, but at the end of the day, vaccine nationalism isn't going to resolve anything in this, because this is a global crisis. and in some ways, yes, it is fantastic that we are doing, or have been doing, incredibly well so far with the vaccination, that is a good thing. but in reality, nobody is safe until everybody is safe, so we need to play our part as well in ensuring that the whole world can access vaccination. but that the whole world can access vaccination.— vaccination. but it isn't 'ust india, vaccination. but it isn't 'ust indie, ti vaccination. but it isn't 'ust india, is it? i vaccination. but it isn't 'ust india, is it? we * vaccination. but it isn't 'ust india, is it? we talk h vaccination. but it isn'tjust india, is it? we talk aboutl vaccination. but it isn'tjust i india, is it? we talk about the czechs that have to be made on the vials that are already here in the country, and that has caused part of the problem. apparently a lot of the vials are made in america, and the stoppers are made in other countries, it feels as, as other companies countries trying to ramp up companies countries trying to ramp up their vaccination programs, that is affecting those people who have already put in orders for certain amounts of vaccine, including the uk? so is there a message that needs to be going to the united states as well, because they are part of the supply chain? i well, because they are part of the supply chain?— supply chain? i think there is a bi aer supply chain? i think there is a bigger point — supply chain? i think there is a bigger point here, _ supply chain? i think there is a bigger point here, and - supply chain? i think there is a bigger point here, and this - supply chain? i think there is a bigger point here, and this is l supply chain? i think there is a i bigger point here, and this is one that we were raising some months ago, that if you spend 30 years not investing in your manufacturing base, and offshoring your manufacturing, then you are pretty exposed when you need access quickly to manufactured materials. we saw this in the ppe crisis earlier last year when we didn't have enough goggles, visors and aprons for our nhs staff. part of the problem is, this country has stopped manufacturing these items. and we were raising months ago with the health secretary, are you sure that we've got enough of the glass vials, are you sure that we've got enough of the stoppers, the gloves and all the paraphernalia that comes along with a big vaccination programme? and we were reassured that all those extras would be there. we are now seeing the demand for these across the world ramping up considerably, and some of this is impacting world supply of the vaccine. now, always can do is hope the pharmaceutical companies —— hold the pharmaceutical companies —— hold the pharmaceutical companies to account and say, you promised us certain amount of supplies, you have got to honour those contracts. but it highlights what a mistake it was for 20—30 years to offshore and not invest in our manufacturing base in this country. we have got to turn that around, we have got to be investing in our manufacturing base again. jonathan ashworth, thanks for joining us, thank you. the care regulator for joining us, thank you. the care regulatorfor england joining us, thank you. the care regulator for england has said hundreds of people had their human rights breached when do not resuscitate decisions were placed on them during the early part of the pandemic. without them or their families knowing about it. a report by the care quality commission says there is some evidence that blanket mention of decisions which restrict potentially life—saving treatment were used on elderly and disabled people. here is nikki jordan is supported by dimensions. this is my support worker, emma. hi. we're currently making an omelette. his social care provider is one of many who have fought to remove inappropriate "do not resuscitate" orders during the pandemic. i want me and my friends to grow old and have a happy and fulfilling life, and to have these decisions made for us, against us, in this way i think is very inhumane. it did create a real climate of fear, i think, amongst people with learning disabilities and their families about what the outcomes might be for people. for the "do not resuscitate" orders that you'd heard about, the inappropriate ones, rachel, what were some of the reasons given? we had somebody we support and the reason given for their order was that they had dyspraxia, asthma and a learning disability, which is clearly entirely inappropriate reasons to apply a "do not resuscitate" order. and there are many examples of this. in fact, the care quality commission was told of more than 500 cases where a "do not resuscitate" order was applied without the consent of the person or their family. it said it raised serious concerns that many disabled people were seeing their human rights breached by not being given the right to choose their own end—of—life care. we know at the beginning of the pandemic there - was a lot of confusion. i think some of that confusion - and some of the miscommunication did lead to this increase in dnr cpr decisions that we saw. - it's completely unacceptable. it'sjust terrifying. your life is everything you own, so, scary. sarah, who wants us to protect her identity, has a rare neuromuscular condition. she's in her early 20s and is a successful writer. at the beginning of the pandemic she was asked on three occasions to sign a "do not resuscitate" order. there was no back—and—forth, it was very much, "i think this should happen to you," it was just, "i think this is best." "they wouldn't treat you anyway, let's do it." it was a tick box exercise. i think of a 20—year—old me, i would have been useless at that conversation. i mean, i have had practice, like, i do use a hospice, but this has felt different. this has felt like a fight, which i really don't enjoy. the government says it will take on board the report's recommendations and stressed that blanket "do not resuscitate" orders were always completely unacceptable. nikki fox, bbc news. let's go back to the situation with vaccinations, and the plaid cymru health spokesman joins us now. thanks for being with us. the health secretaries of england and scotland are confident that they will be able to get through the numbers of people that they projected, despite these supply problems, are you as confident in wales?- supply problems, are you as confident in wales? well, what i have done _ confident in wales? well, what i have done throughout _ confident in wales? well, what i have done throughout the - confident in wales? well, what i - have done throughout the pandemic, i think we need to ask again for total openness and transparency, in this case, on what the impact of delayed supply will be, how that will need to change the plans for the vaccination programme for the weeks ahead. we need the full sweet of data so that people can understand what's going on, where vaccines are flowing to, to make sure that there is real fairness, flowing to, to make sure that there is realfairness, and that flowing to, to make sure that there is real fairness, and that things are working as quickly as they can. are you in any position get to lay out a roadmap for the full unlocking of wales? ~ . ., , ., , ., of wales? well, certainly as far back as early — of wales? well, certainly as far back as early last _ of wales? well, certainly as far back as early last summer, - of wales? well, certainly as far back as early last summer, i i of wales? well, certainly as far. back as early last summer, i have been calling on the welsh government to be as clear as possible about what is likely to happen in the weeks and months ahead. i still don't quite see how the uk prime minister can say this is going to happen on a particular day injuly, because that seems a bit far away. but we need to know what is going to be happening in a few weeks' time. what people can plan to expect if things keep on track. and i still calling on the welsh government to do that, be it for the benefit of business which needs to get going again, but also for welfare. people are struggling and they need to know when they are going to be able to take that pressure off themselves and their families.— take that pressure off themselves and their families. indeed, because, as i and their families. indeed, because, aslsa , and their families. indeed, because, as i say. england — and their families. indeed, because, as i say, england seems _ and their families. indeed, because, as i say, england seems to - and their families. indeed, because, as i say, england seems to have - and their families. indeed, because, as i say, england seems to have a i as i say, england seems to have a roadmap, scotland seems to have a roadmap, scotland seems to have a roadmap, wales does not seem to be there, is that surprising to you? well, i think the welsh government has missed an opportunity many times. last year, i referred to the republic of ireland, which i thought was doing really well at that time getting a real roadmap ahead, when the labour government in wales were very reticent to do that. i am not saying, tell us what is happening in concrete on a particular date two months from now, but we were in a situation last week where we had businesses on a friday waiting for the first minister to get on his feet, not really sure if they were going to be open on monday. now, that's not good enough, really. i think with caveats, that if things go particularly wrong, because this virus can throw all sorts of curveballs virus can throw all sorts of cu rveballs at virus can throw all sorts of curveballs at us, but with caveats like that, people should have that kind of warning of what is go to be happening, so that businesses can plan and people like you and me can think, what kind of freedoms we are likely to get in the weeks ahead. but it is about data, not dates, isn't it? , ., ., isn't it? exactly and there are basic bits _ isn't it? exactly and there are basic bits of _ isn't it? exactly and there are basic bits of data _ isn't it? exactly and there are basic bits of data that - isn't it? exactly and there are basic bits of data that i - isn't it? exactly and there are basic bits of data that i think| isn't it? exactly and there are i basic bits of data that i think we need. in my constituency people say they are getting the vaccine before us, within wales, people saying, down in that part of wales they are getting it before us. and it happens across the uk as well. i have been calling for complete transparency on how much of which vaccine is flowing to which country and when, so we can be clear that things are happening fairly and that everybody has a fair crack of the web.— fairly and that everybody has a fair crack of the web. what seems to be clear is that — crack of the web. what seems to be clear is that the _ crack of the web. what seems to be clear is that the uk _ crack of the web. what seems to be clear is that the uk medicines - clear is that the uk medicines agency and now the european medicines agency, the regulators are all saying the astrazeneca vaccine is safe, briefly?— all saying the astrazeneca vaccine is safe, briefly? yes, this is good. i fully understand _ is safe, briefly? yes, this is good. i fully understand why _ is safe, briefly? yes, this is good. i fully understand why people - is safe, briefly? yes, this is good. i i fully understand why people might be nervous, it's quite normalfor people to want to ask questions about the safety of vaccines, but i think even a pretty basic look at the statistics, the chances of you developing a blood clot, if you get covid, compared with... i am going to have to — covid, compared with... i am going to have to interrupt _ covid, compared with... i am going to have to interrupt you _ covid, compared with... i am going to have to interrupt you there, - covid, compared with... i am going to have to interrupt you there, i i covid, compared with... i am going to have to interrupt you there, i do | to have to interrupt you there, i do apologise, sorry about that. time for a look at the weather. hello. there's very little happening on the weather front across the uk in the coming days. it's going to essentially stay more or less the same from day—to—day. there will be a little bit of sunshine developing, but on the whole, pretty cloudy. on the satellite picture, you can see where the clouds are coming from. they are drifting in from the norwegian sea, riding around this area of high pressure which is parked to the west, southwest of ireland and this is where the high pressure is more or less going to stay over the next few days. you can see the air currents, the wind blowing around the higher, the wind blowing around the high, hence the cloud is coming in from the north, but it tends to break up in a few areas. but in other areas, it is thick enough to produce rain. we've had rain in the last day or so. there could be more damp weather anywhere from eastern parts of england, through the east midlands and into the southeast as well, but frost—free for most of us, perhaps a touch of frost where the sky is clear in the coming days. notice tomorrow, there is a very definitive edge between drier, sunnier weather coming in out of the continent and this thicker cloud across the rest of the country. the thinking is from hull to london and southampton there will be sunshine developing on friday afternoon, somewhat drier air heading our way, evaporating those clouds. the high pressure's still with us on saturday, which is the first day of astronomical spring, the vernal equinox, so we well and truly are into spring, but the weather isn't changing much. the wind still blowing out of the north across scotland, perhaps a spot of rain for stornoway. for the rest of the country, it's a case of variable amounts of cloud and this high pressure is still with us through the weekend into next week. the jet stream is way to the north of us, sending the unsettled weather in the direction of iceland and also around the mediterranean, but we're closer to that high. so, little change, and take a look at this outlook for the next few days. the weather icons indicating clouds or variable amounts of cloud — very difficult to actually indicate on a symbol — with temperatures hovering between 11—13c. the weather will change, but not until later next week. that's it from me. bye— bye. today at six — the eu medical regulator gives the astrazeneca vaccine the green light. several eu countries had suspended jabs while they tried to find out if there was a link to blood clots. this is a safe and effective vaccine. its benefits in protecting people from covid—19 with the associated risks of death and hospitalisation outweigh the possible risks. here, despite a problem with supplies from india, no vaccination appointments will be cancelled. our progress along the road to freedom continues unchecked. we remain on track to reclaim the things we love, to see our families and friends again. the prime minister says he'll be getting the oxford jab tomorrow. also tonight — the american private investigator, who was paid by the sun for information on meghan markle — he says he broke the law.

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