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Masculinizing Hormone Therapy Tied to Acne in Transmen

Acne was a common occurrence after initiating masculinizing hormone therapy (MHT), researchers reported. In a retrospective analysis of nearly 1,000 transgender individuals who started MHT, prevalence of acne jumped from just 6.3% to 31.1% after an average therapy duration time of 3.4 years, according to Erica Dommasch, MD, MPH, of Beth Israel Deaconess Medical Center in Boston, and colleagues. The rate of new acne diagnoses peaked within the first 6 months after starting MHT, they wrote in However, in the years following hormone therapy initiation, acne continued to become more widespread. In the first year of initiating hormones, the proportion of individuals with acne jumped to 19% and then rose to 25.1% after 2 years.

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