The motorcycle rider, a 28-year-old Karalee man, was initially treated at the scene in a critical condition.
The man died at the scene.
The 48-year-old driver of the Nissan Navara and his 13-year-old passenger were not physically injured during the crash.
Police have appealed to those who may have seen either vehicles prior to the incident or anyone who may have stopped at the intersection and witnessed the incident to contact them.
Forensic Crash Unit investigations are investigating.
Anyone with information can call Crime Stoppers on 1800 333 000.
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