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Novartis exhorté à coopérer sur la recherche et la production de médicaments

Novartis exhorté à coopérer sur la recherche et la production de médicaments
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Novartis launches trial to test ensovibep as COVID treatment

The EMPHATHY clinical trial will enroll patients with COVID-19 to test the drug’s effectiveness in preventing worsening of symptoms and hospitalization. Novartis and Molecular Partners have announced the start of their EMPATHY Phase II/III study to explore the use of its DARPin (designed ankyrin repeat proteins) therapeutic candidate ensovibep (MP0420) for the treatment of COVID-19. Novartis reportedly will run the trial program, with Molecular Partners serving as sponsor. The EMPATHY clinical trial program is intended to investigate the safety and efficacy of ensovibep in COVID-19 in the early stages of infection, with the goal of worsening symptoms and hospitalization. According to the companies, the study will enroll 400 patients in Phase II to determine a dose with optimal safety and activity; initial results are expected in August 2021.

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