New adaptable nanoparticle platform enables enhanced delivery of gene therapies, RCSI research
DULBIN, June 9, 2021 /PRNewswire/ Scientists have developed polypeptide-based materials that act as effective vectors for delivering gene therapies. The first-of-its-kind platform enables the vectors to be adapted to suit the specific gene therapy cargo.
The work, led by researchers from RCSI University of Medicine and Health Sciences and funded by Science Foundation Ireland, is published in Biomaterials Science.
A major challenge for gene therapies is preparing them in a way that can deliver the genetic information into the host cells. For the Covid-19 vaccines that use mRNA technology, the genetic information is delivered in a lipid nanoparticle to maintain its stability and deliver it into cells. The success of the COVID vaccines has established nanoparticles as key to the development of many advanced therapies.
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There s No Such Thing as an Easy Job, Kikuko Tsumura s first novel translated into English
12 Mar, 2021 08:00 PM
3 minutes to read
By: Kiran Dass With multiple lockdowns and the shift to many people working from home and workplaces becoming more flexible and adaptable over the past year, many people s attitudes to what pop philosopher Alain de Botton refers to as the pleasures and sorrows of work has shifted dramatically. Work is a four-lettered word, and workers are becoming increasingly aware of burnout and the quest for more meaningful work.
This is the first novel translated into English (by Polly Barton) from the Japanese by Osaka-based writer Kikuko Tsumura. It s been compared to acclaimed books My Year of Rest and Relaxation by Ottessa Moshfegh and Convenience Store Woman by Sayaka Murata – and, like those novels, it will chime with anyone suffering late-capitalism fatigue, workplace burnout and employment precarity anxiety.
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