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Access to essential cancer medicines unequal across countries
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New method to detect and visualise sperm cells recovered from forensic evidence
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King’s College London
New gel technology achieves enhanced brain delivery of a Parkinson’s Disease drug.
A team of researchers from the School of Cancer & Pharmaceutical Sciences at King’s, led by Professor Khuloud Al-Jamal, Head of Medicines Development at the Institute of Pharmaceutical Science, have been working collaboratively with researchers from the University of York to optimise the brain uptake of a new gel designed to treat Parkinson’s Disease.
Parkinson’s Disease is a debilitating and progressive neurodegenerative disease. Over 100,000 people live with the condition in the UK and it’s the fastest growing neurological condition in the world. The main symptoms of the disease are tremor, stiffness, and slowness of movement.
King’s College London
Plant-derived agent shows promise in the treatment of malaria.
Malaria is caused by the parasite Plasmodium which is transferred to humans by mosquitos feeding on blood. Plasmodium has evolved to evade the human immune system and survive and replicate inside the body.
One of these immune evasion mechanisms involves the activation of a particular protein called TGFbeta as soon as the parasite enters the blood. TGFbeta then switches the immune system from killing infected cells to killing bacteria; one way that the parasite can survive within the host environment.
Vernonia Amygdalina is a species of plant found predominantly in sub-Saharan Africa, using medicinally by local communities for a variety of diseases, including malaria. Research by Dr Richard Beatson from the School of Cancer & Pharmaceutical Sciences is working to identify the active agent.
Pfizer vaccine provides less protection in cancer patients after a single dose, study finds
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