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COVID-19 vaccine development built on >$17 billion in NIH funding for vaccine technologies

Credit: © Center for Integration of Science and Industry at Bentley University The unprecedented development of COVID-19 vaccines less than a year after discovery of this virus was enabled by more than $17 billion of research on vaccine technologies funded by the NIH prior to the pandemic, according to new research from Bentley University sCenter for Integration of Science and Industry. The article, titled NIH funding for vaccine readiness before the COVID-19 pandemic, demonstrates the critical role this broad foundation of government-funded research plays in ensuring vaccine readiness. The report, published today in the journal Vaccine, examined the maturation of research and NIH funding for ten technologies that were applied in candidate COVID-19 vaccines as of July 2020. The maturation of these technologies was described in 51,530 published research papers from 2000-2019, of which 8,420 (16%) acknowledge NIH funding totaling $17.2 billion. Some of these technologies have be

Investment risk & return from emerging public biotech companies comparable to non-biotech

 E-Mail IMAGE: Shareholder value at the end of 2016 compared to IPO for biotech companies and paired controls completing IPOs 1997-2016. Net growth in shareholder value, and the fraction of companies generating. view more  Credit: Center for Integration of Science and Industry, Bentley University Investing in biotech companies may not entail higher risk than investing in other sectors, according to a new report from Bentley University s Center for Integration of Science and Industry. A large scale study of biotechnology companies that completed Initial Public Offerings (IPOs) from 1997-2016 demonstrates that these companies produced more than $100 billion in shareholder value and almost $100 billion in new value creation despite a failure rate greater than 50%. The study compared the financial performance and economic value created by these biotech companies to non-biotechnology controls that had similarly timed IPOs.

Majority of biotech companies completing an IPO from 1997-2016 achieved product approvals

 E-Mail IMAGE: Estimated probability (Kaplan-Meier) of a company with IPO from 1997-2016 having at least one product approved by year after IPO for small molecules versus biologicals. view more  Credit: Center for Integration of Science and Industry, Bentley University A large scale study from Bentley University of the biotechnology companies that completed Initial Public Offerings from 1997-2016 estimates that 78% of these companies are associated with products that reach phase 3 trials and 52% are associated with new product approvals. The article, titled Late-stage product development and approvals by biotechnology companies after IPO, 1997-2016, shows that these emerging, public biotechnology companies continue to have a role in initiating new product development, but are no longer distinctively focused on novel, biological products.

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