Day Five of Bionano’s Next-Generation Cytogenomics Symposium: Saphyr Identifies Structural Variants that May Predispose to Severe COVID-19 Illness
January 18, 2021 19:00 ET | Source: Bionano Genomics Bionano Genomics San Diego, California, UNITED STATES
COVID-19 Host Genome Structural Variant (SV) Consortium used Saphyr to identify SVs in severe COVID-19 patients that affect genes involved in immunity, airway mucous, and viral replication
SVs found by several investigators point to a central role for disease severity of the interferon response pathway
Consortium has added investigators from Augusta University, Boston Children’s Hospital, New York Genome Center, Radboud University, Rockefeller University, UC San Diego, Virginia Commonwealth University, and two dozen other institutes from around the world
drug resistance in cancer cincinnatisun.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from cincinnatisun.com Daily Mail and Mail on Sunday newspapers.
Scientists unveil mystery behind drug resistance in cancer through ecDNA forms ANI | Updated: Dec 27, 2020 21:55 IST
Washington [US], December 27 (ANI): Researchers from Sanger Center here claimed that the free-floating circular DNA fragments, found in cancer cells, generate drug resistance in cancer.
Published in the journal Nature, a study provides new insights into how cancers evolve to adapt to changing environments and suggests ways to reduce drug resistance by combining therapies. Drug resistance is the most problematic part of cancer therapy. If not for drug resistance, many cancer patients would survive, said Ofer Shoshani, a postdoctoral researcher in Cleveland s lab and the study s first author.
Study reveals how ecDNA fragments drive gene amplification to generate drug resistance in cancer
Researchers led by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the mystery of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to generate drug resistance in cancer.
The research, published on December 23 in the journal
Nature, provides new insights into how cancers evolve to adapt to changing environments and suggests ways to reduce drug resistance by combining therapies.
Drug resistance is the most problematic part of cancer therapy. If not for drug resistance, many cancer patients would survive.
Study reveals how ecDNA forms, drives cancer drug resistance ANI | Updated: Dec 24, 2020 11:54 IST
Washington [US], December 24 (ANI): Researchers led by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the mystery of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to generate drug resistance in cancer.
The research, published in the journal Nature, provides new insights into how cancers evolve to adapt to changing environments and suggests ways to reduce drug resistance by combining therapies. Drug resistance is the most problematic part of cancer therapy. If not for drug resistance, many cancer patients would survive, said Ofer Shoshani, a postdoctoral researcher in Cleveland s lab and the study s first author.