Scientists unveil mystery behind drug resistance in cancer through ecDNA forms
ANI |
Updated: Dec 27, 2020 21:55 IST
Washington [US], December 27 (ANI): Researchers from Sanger Center here claimed that the free-floating circular DNA fragments, found in cancer cells, generate drug resistance in cancer.
Published in the journal Nature, a study provides new insights into how cancers evolve to adapt to changing environments and suggests ways to reduce drug resistance by combining therapies.
"Drug resistance is the most problematic part of cancer therapy. If not for drug resistance, many cancer patients would survive," said Ofer Shoshani, a postdoctoral researcher in Cleveland's lab and the study's first author.