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Gesundheits-Tipp: Wenn der Harnsäurewert steigt

Gesundheits-Tipp: Wenn der Harnsäurewert steigt Menschen, die zu Gichtanfällen neigen, sollten sich fleischarm ernähren. Auch Alkohol mindert die Harnsäure-Ausscheidung, sagt die Darmstädter Ärztin Nina Leitsch. Von Nina Leitsch Jetzt teilen: Jetzt teilen: DARMSTADT - Im Stoffwechsel fallen ständig wasserlösliche Abbauprodukte an, die in höheren Konzentrationen schädlich wären und daher über die Nieren ausgeschieden werden. Eines davon ist die Harnsäure. Sie entsteht, wenn sogenannte Purine verstoffwechselt werden. Purine sind vor allem in tierischen und in pflanzlichen Zellen enthalten. Normalerweise liegt der Harnsäurespiegel im Blut unter sechs Milligramm pro Deziliter. Manche Labore verwenden die Einheit Mikromol pro Liter. Das entspricht einem Grenzwert von unter 360. Steigt der Spiegel über diesen Wert, kann das Blut die Harnsäure nicht mehr ausreichend lösen. Dann

Cytokine Hurricane in Lung may Damage Inflammatory Cells

Cytokine Hurricane in Lung may Damage Inflammatory Cells by Angela Mohan on  March 16, 2021 at 3:19 PM Cytokine hurricane centered in the lungs drives respiratory symptoms in patients with severe COVID-19. Two cytokines, CCL2 and CCL3, appear critical in luring immune cells, called monocytes, from the bloodstream into the lungs, where the cells launch an overaggressive attempt to clear the virus. Targeting these specific cytokines with inhibitors may calm the immune reaction and prevent lung tissue damage. Currently, one drug that blocks immune responses to CCL2 is being studied in clinical trials of patients with severe COVID-19. Survivors of severe COVID-19, the study also found, had a greater abundance of antiviral T cells in their lungs than patients who died, suggesting these T cells may be critical in helping patients control the virus and preventing a runaway immune response.

Can Biomarkers Determine Who s at Risk for Severe Covid-19 Symptoms?

by Hannah Joy on  February 11, 2021 at 6:31 PM Yes, biomarkers can help determine who s at risk for severe covid-19 symptoms by combining metabolomics and machine learning, reveal researchers reporting in ACS Analytical Chemistry. One of the many mysteries still surrounding COVID-19 is why some people experience only mild, flu-like symptoms, whereas others suffer life-threatening respiratory problems, vascular dysfunction and tissue damage. Although some pre-existing conditions, such as diabetes or obesity, can increase the risk of hospitalization and death from COVID-19, some otherwise healthy people have also experienced severe symptoms. ‘Biomarkers help to know why some people affected with Covid-19 experience only mild, flu-like symptoms, while others suffer life-threatening respiratory problems, vascular dysfunction and tissue damage.’

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