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IMAGE: Students at St. Georges Technical High School in Middletown, Delaware are the first high school students in the United States to use the innovative CRISPR in a Box educational gene. view more
Credit: ChristianaCare
St. Georges Technical High School in southern New Castle County, Delaware is the first high school in the United States to use ChristianaCare Gene Editing Institute s innovative CRISPR in a Box Educational Toolkit™ in a science class.
CRISPR in a Box brings to life the much-heralded CRISPR gene editing technology - the genetic scissors that allow scientists to edit DNA. The toolkit is designed for educational sessions in secondary and post-secondary schools and is suitable for remote learning.
A Penn Medicine patient with a genetic form of childhood blindness gained vision, which lasted more than a year, after receiving a single injection of an experimental RNA therapy into the eye.
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SEATTLE (April 1, 2021) - An international consortium of geneticists, biologists, clinicians, mathematicians, and other scientists is determined to take the study of the human genome to the next level - creating a comprehensive atlas of genetic variants to advance the understanding, diagnosis, and treatment of disease. This Herculean undertaking is unprecedented, said Dr. Matthew Hurles, a geneticist at the Wellcome Sanger Institute in Cambridge, England. Indeed, the scientific community has an increasingly comprehensive catalog of functional DNA elements in the human genome, but that catalog remains incomplete. We have collectively characterized the functional impact of less than 1% of genetic variation in the 1 to 2 percent of our DNA.
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IMAGE: In this image of a neuron nucleus, bright spots show areas of focused genetic repair. view more
Credit: Salk Institute/Waitt Advanced Biophotonics Center
LA JOLLA (April 1, 2021) Neurons lack the ability to replicate their DNA, so they re constantly working to repair damage to their genome. Now, a new study by Salk scientists finds that these repairs are not random, but instead focus on protecting certain genetic hot spots that appear to play a critical role in neural identity and function.
The findings, published in the April 2, 2021, issue of
Science, give novel insights into the genetic structures involved in aging and neurodegeneration, and could point to the development of potential new therapies for diseases such Alzheimer s, Parkinson s and other age-related dementia disorders.