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Gene therapy for macular degeneration? - Innovation Toronto

Experimental Gene Therapy Helps Restore Night Vision in People With Form of Childhood Blindness

Adults with a genetic form of childhood-onset blindness experienced striking recoveries of night vision within days of receiving an experimental gene therapy, according to researchers.

Gene therapy shows promise for patients with congenital blindness

Gene Therapy Shows Promise in Congential Blindness Patients

Gene Therapy Shows Promise in Congential Blindness Patients by Angela Mohan on  April 20, 2021 at 11:14 AM New gene therapy for a congenital blindness was found to be safe and improved patients vision, according to a clinical trial led by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania. This gene therapy delivers copies of GUCY2D gene to the eyes of patients who have severe vision impairments caused by mutations in the gene, according to the study, published in the journal iScience. We found sustained improvements in both day and night vision, even with a relatively low dose of the gene therapy, said study lead author Samuel G. Jacobson, MD, PhD, a professor of Ophthalmology in the Perelman School of Medicine.

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