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Combined approach could boost breast cancer immunotherapy, study suggests

 E-Mail IMAGE: A diagram showing the various strategies that could enhance the activity of CAR T cells against breast cancer. view more  Credit: © 2020 Xu et al. Originally published in Journal of Experimental Medicine. https://doi.org/10.1084/jem.20200844 Activating an immune signaling pathway best known for fighting viral and bacterial infections can boost the ability of genetically engineered T cells to eradicate breast cancer in mice, according to a new study by researchers at the University of North Carolina. The study, to be published December 31 in the JEM), suggests that CAR T cells, which are already used to treat certain blood cancers in humans, may also be successful against solid tumors if combined with other immunotherapeutic approaches.

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