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It’s a nightmare scenario: A coronavirus variant escapes science’s cleverly constructed defenses and returns to spreading unchecked, sending more than a year’s work to develop and administer billions of vaccine doses up in smoke.  The most recent cause for alarm is the highly infectious Delta variant, first identified in India, which is pushing up case numbers again in countries like the U.K. and Portugal, prompting some EU countries to issue a new round of travel restrictions. But for now, public health experts say, it s not time to panic. So far, most argue, the chances of a runaway coronavirus mutation dodging the protective effects of a vaccine known as an escape variant appear slim even though some variants might swerve around immune defenses somewhat.

United statesUnited kingdomSouth africaCity ofSouth africanGary mcleanEli lillyDavid heymannAndreas radbruchChris whittyCharles banghamDanny altmannBoris johnsonImmunology at imperial college londonLondon school of hygiene tropical medicineImperial college london