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Žarnyne trūksta gerųjų bakterijų? Kyla rizika susirgti su tokiomis ligomis kaip Alzheimeris ir Parkinsonas
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Written by James Kingsland on May 11, 2021 â Fact checked by Rita Ponce, Ph.D.
A new study in worms investigates links between gut bacteria and protein clumping. Reptile8488/Getty Images
Previous research has found links between gut bacteria and degenerative brain disorders, such as Parkinsonâs disease, Alzheimerâs
disease, and amyotrophic lateral sclerosis (ALS).
A new study in tiny worms provides the first evidence that âpathogenicâ bacteria can promote the misfolding of proteins that is a characteristic of these conditions.
Other bacteria that produce a fatty acid called butyrate prevented protein misfolding in the worms.
The research adds to evidence that a history of antibiotic treatments may play a role in the early development and course of Parkinsonâs disease.
Researchers have established, for the first time, a link between specific gut bacteria species and physical manifestations of neurodegenerative diseases.
Neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS affect millions of adults, but scientists still do not know what causes these diseases, which poses a significant roadblock to developing treatments or preventative measures.
Recent research suggests that people with these conditions exhibit changes in the bacterial composition of their digestive tract. However, given the vast diversity of microbes found in the human body, identifying which bacteria may be associated with neurodegeneration is like finding a needle in a haystack.