Dementia, Parkinson's: Is there a role for gut bacteria?

Written by James Kingsland on May 11, 2021 — Fact checked by Rita Ponce, Ph.D.
A new study in worms investigates links between gut bacteria and protein clumping. Reptile8488/Getty Images
Previous research has found links between gut bacteria and degenerative brain disorders, such as Parkinson’s disease, Alzheimer’s
disease, and amyotrophic lateral sclerosis (ALS).
A new study in tiny worms provides the first evidence that “pathogenic” bacteria can promote the misfolding of proteins that is a characteristic of these conditions.
Other bacteria that produce a fatty acid called butyrate prevented protein misfolding in the worms.
The research adds to evidence that a history of antibiotic treatments may play a role in the early development and course of Parkinson’s disease.

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