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Chemotherapy destabilizes gut microbiome in cancer patients
New research in
BMC Cancer has shown myelosuppressive chemotherapy destabilizes gut microbiome in patients with solid organ cancers.
The study from SAHMRI and Flinders University assessed the gut health of men and women who underwent conventional chemotherapy on cancers, such as breast and lung cancer, without exposure to antibiotics. We know that myelosuppressive chemotherapy reduces white blood cell count significantly during the first seven to 10 days of treatment, making the body more vulnerable to infection, says lead author Dr Lito Papanicolas, an infectious diseases expert and clinical microbiologist. In this study we focused on how much the individual s microbiome changed over this period, when the bacteria are most likely to cause infection.
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