From left: Hongbo Chi, Ph.D., Hongling Huang, Ph.D., and PeiPei Zhou, Ph.D., all of St. Jude Immunology, have mapped the previously unknown biological.
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Discovery offers potential for stripping tumors of T cell protection
First author Seon Ah Lim, Ph.D., and corresponding author Hongbo Chi, Ph.D., both of St. Jude Immunology, contributed to research that raises the potential for treatments that render tumors more vulnerable to cancer immunotherapy.
Immunologists at St. Jude Children’s Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system. Surprisingly, the mechanism does not affect regulatory T cell function outside the tumor and may therefore limit the immune-associated toxicities of targeting regulatory T cells.
CHINA / IN-DEPTH
China’s Generation Z redefines trendy, shows growing faith in local culture By GT staff reporters Published: Jan 14, 2021 07:03 PM
Young people visit the Bilibili booth at ChinaJoy in Shanghai on August 1, 2020 Photo: ICTwenty years ago, many young people in China who were first exposed to Western culture thought rebelling against traditional Chinese culture and mimicking foreign culture was fashionable and trendy. But this view is outdated for Generation Z today - a generation who grew up with China s rapid development - who now redefines what trendy is by promoting local culture while having an objective view of exotic cultural products.