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Scientists uncover key to enhancing cancer-killing T cells

T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a hypofunctional state known as exhaustion.

Jordy saraviaPeipei zhouShondra pruett millerHongbo chiHongling huangNicole chapmanJonp connellyXiang sunZhao shiCancer center support grantNational institutes of healthJude children research hospitalJude department of immunologyJude childrenResearch hospitalJude department

T cells in the brain slow progression of Alzheimer s

Scientists have found that a subset of CD8<sup>+</sup> T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer's disease.

Jordy saraviaHongbo chiWei suJude children research hospitalJude childrenResearch hospitalAlzheimer amp 39 sSt jude childrens research hospitalNature immunologyCd8t cellsImmune cells

How specific T cells in brain slow progression of Alzheimer s disease: Study | Health

The study states how T cells helps in slowing down Alzheimer’s by interacting with microglia - immunological cells in brain that remove beta-amyloid plaques. | Health

United statesHongbo chiWei suJordy saraviaJude department of immunologyJude children research hospitalJude childrenResearch hospitalJude departmentAlzheimer diseaseAlzheimer sAlzheimers diseaseSlow progression of alzheimers diseaseT cells in brain slow progression of alzheimers disease

Study finds how specific T cells in brain slow progression of Alzheimers disease

Study finds how specific T cells in brain slow progression of Alzheimers disease
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United statesJordy saraviaWei suHongbo chiJude children research hospitalJude department of immunologyJude childrenResearch hospitalJude department

Study finds how specific T cells in brain slow progression of Alzheimer s disease

Study finds how specific T cells in brain slow progression of Alzheimer s disease
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United statesWei suHongbo chiJordy saraviaJude children research hospitalJude department of immunologyJude childrenResearch hospitalJude department