Urine Samples Detect MicroRNAs Biomarkers For Heart And Kidney Disease by Karishma Abhishek on March 2, 2021 at 8:35 AM Epigenomics. regulating gene expression. They are readily explored in diagnosing various diseases at present. For the first time, we measured in healthy children the associations between urinary miRNAs and cardiorenal outcomes, including blood pressure, urinary sodium and potassium levels, and eGFR [estimated glomerular filtration rate, a measure of how well the kidneys are filtering or cleaning the blood]. These relationships represent an opportunity to develop novel biomarkers for early detection and treatment of kidney damage or dysfunction , says lead author Yuri Levin-Schwartz, Ph.D., a postdoctoral fellow in the Department of Environmental Medicine and Public Health at the Icahn School of Medicine at Mount Sinai.
MicroRNA Testing of Healthy Children Could Provide a Window on Heart and Kidney Health Later in Life
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MicroRNAs predict heart and kidney health in children without disease
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New York, NY (February 26, 2020) - Molecules called microRNAs (miRNAs) that are measurable in urine have been identified by researchers at Mount Sinai as predictors of both heart and kidney health in children without disease. The epidemiological study of Mexican children was published in February in the journal
Epigenomics. For the first time, we measured in healthy children the associations between urinary miRNAs and cardiorenal outcomes, including blood pressure, urinary sodium and potassium levels, and eGFR [estimated glomerular filtration rate, a measure of how well the kidneys are filtering or cleaning the blood], says lead author Yuri Levin-Schwartz, PhD, a postdoctoral fellow in the Department of Environmental Medicine and Public Health at the Icahn School of Medicine at Mount Sinai. These relationships represent an opportunity to develop novel biomarkers for early detection and treatment of kidney damage or dysfunction.