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Urine Test Helps Detect Kidney Transplant Rejection by Karishma Abhishek on March 9, 2021 at 8:23 AM
Twenty percent of patients experience kidney transplant rejection even after a long waiting time till 6years. The recipient s immune cells recognize the newly received kidney as a foreign organ and thus on refusing the acceptance of the donor s antigens, results in transplant rejection. invasive biopsy procedures, (that requires multiple days of hospitalization and risks of complications) or creatinine blood tests (do not always yield definitive results). Moreover 70-80 percent of biopsies end up being normal.
To overcome these hurdles, a new easier alternate way that is
Urine Samples Detect MicroRNAs Biomarkers For Heart And Kidney Disease by Karishma Abhishek on March 2, 2021 at 8:35 AM Epigenomics. regulating gene expression. They are readily explored in diagnosing various diseases at present. For the first time, we measured in healthy children the associations between urinary miRNAs and cardiorenal outcomes, including blood pressure, urinary sodium and potassium levels, and eGFR [estimated glomerular filtration rate, a measure of how well the kidneys are filtering or cleaning the blood]. These relationships represent an opportunity to develop novel biomarkers for early detection and treatment of kidney damage or dysfunction , says lead author Yuri Levin-Schwartz, Ph.D., a postdoctoral fellow in the Department of Environmental Medicine and Public Health at the Icahn School of Medicine at Mount Sinai.