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Objective To investigate the risk of non-alcoholic fatty liver disease (NAFLD) for cardiovascular disease and all cause death in patients with type 2 diabetes mellitus (T2DM). Design Nationwide population based study. Setting Longitudinal cohort study in Korea. Participants 7 796 763 participants in the National Health Screening Programme in 2009 were divided into three groups based on NAFLD status: no NAFLD (fatty liver index<30); grade 1 NAFLD (30≤fatty liver index<60); and grade 2 NAFLD (fatty liver index≥60). Median follow-up was 8.13 years. Main outcome measures The primary outcome was incident cardiovascular disease (myocardial infarction, ischaemic stroke) or all cause death. Results Of 7 796 763 participants, 6.49% (n=505 763) had T2DM. More patients with T2DM had grade 1 NAFLD (34.06%) and grade 2 NAFLD (26.73%) than those without T2DM (grade 1 NAFLD: 21.20%; grade 2 NAFLD: 10.02%). The incidence rate (per 1000 person years) of cardiovascular disease a

Kyung soo kimSangmo hongKyungdo hanNational health information databaseNational death registrySoongsil universityNational health insurance serviceNational health screening programmeYoung parkIcy parkNational health screeningNational deathChronic kidney disease epidemiology collaborationOpen accessCreative commons attribution non commercial