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Researchers discover a vulnerability in immunotherapy-resistant triple-negative breast cancer

Researchers at Vanderbilt-Ingram Cancer Center have discovered a druggable target on natural killer cells that could potentially trigger a therapeutic response in patients with immunotherapy-resistant, triple-negative breast cancer.

Immunotherapy-Resistant Breast Cancer: New Vulnerability Found

Immunotherapy-Resistant Breast Cancer: New Vulnerability Found
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Vulnerability found in immunotherapy-resistant triple-negative breast cancer

Vulnerability found in immunotherapy-resistant triple-negative breast cancer
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Druggable Target Discovered in Immunotherapy-Resistant Triple-Negative Breast Cancer

Druggable Target Discovered in Immunotherapy-Resistant Triple-Negative Breast Cancer
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Cardiac Antigen Identified as Mechanism for Heart Complication

(HEALTH NEWS) Myocarditis is a complication that can occur in cancer patients treated with immune checkpoint inhibitors. Although the adverse event is rare — affecting less than 1% of patients given the immunotherapy — the mortality rate is nearly 50%. Now, researchers from Vanderbilt-Ingram Cancer Center have identified the mechanism for the deadly heart inflammation. The researchers discovered that T-cells recognizing the cardiac antigen α-myosin are the mechanism for this .

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