Immunotherapy-Resistant Breast Cancer: New Vulnerability Found
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Vulnerability found in immunotherapy-resistant triple-negative breast cancer
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Druggable Target Discovered in Immunotherapy-Resistant Triple-Negative Breast Cancer
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(HEALTH NEWS) Myocarditis is a complication that can occur in cancer patients treated with immune checkpoint inhibitors. Although the adverse event is rare — affecting less than 1% of patients given the immunotherapy — the mortality rate is nearly 50%.
Now, researchers from Vanderbilt-Ingram Cancer Center have identified the mechanism for the deadly heart inflammation.
The researchers discovered that T-cells recognizing the cardiac antigen α-myosin are the mechanism for this .