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Obesity Paradox of Cancer Immunotherapy Response Linked to Immune Checkpoint Protein on Macrophages

Obesity Paradox of Cancer Immunotherapy Response Linked to Immune Checkpoint Protein on Macrophages
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Obesity-cancer connection discovery suggests strategies for improving immunotherapy

Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer. The findings provide a mechanistic explanation for how obesity can contribute to both increased cancer risk and enhanced responses to immunotherapy.

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