New study provides both good and bad news about transient ischemic attacks
Study findings released Tuesday in the
Journal of the American Medical Association (JAMA) hold both good news and bad news about transient ischemic attacks (TIAs), which are harbingers of subsequent strokes.
Sudha Seshadri, MD, professor of neurology at The University of Texas Health Science Center at San Antonio and director of the university s Glenn Biggs Institute for Alzheimer s and Neurodegenerative Diseases, is senior author of the study and senior investigator of the Framingham Heart Study, from which the findings are derived.
She said the extensive follow-up of Framingham participants over more than six decades enabled the study to present a more-complete picture of the risk of stroke to patients after a TIA.
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Past decades of progress in secondary prevention for transient ischemic attack (TIA) patients were not enough to fully mitigate their elevated risk of subsequent stroke, a longitudinal study showed.
In the Framingham Heart Study, TIA incidence was 1.19 per 1,000 person-years from 1948 through 2017 among 14,059 people with no prior TIA or stroke history, according to Vasileios-Arsenios Lioutas, MD, of Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, and colleagues.
The 435 people who had experienced a TIA had a subsequent stroke in nearly 30% of cases within 9 years their estimated 10-year cumulative stroke risk ended up being more than quadruple that of matched TIA-free controls (hazard 0.46 vs 0.09, adjusted HR 4.37, 95% CI 3.30-5.71), they reported online in
SAN ANTONIO and BOSTON - Study findings released Tuesday in the
Journal of the American Medical Association (JAMA) hold both good news and bad news about transient ischemic attacks (TIAs), which are harbingers of subsequent strokes.
Sudha Seshadri, MD, professor of neurology at The University of Texas Health Science Center at San Antonio and director of the university s Glenn Biggs Institute for Alzheimer s and Neurodegenerative Diseases, is senior author of the study and senior investigator of the Framingham Heart Study, from which the findings are derived. She said the extensive follow-up of Framingham participants over more than six decades enabled the study to present a more-complete picture of the risk of stroke to patients after a TIA.