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Past decades of progress in secondary prevention for transient ischemic attack (TIA) patients were not enough to fully mitigate their elevated risk of subsequent stroke, a longitudinal study showed.
In the Framingham Heart Study, TIA incidence was 1.19 per 1,000 person-years from 1948 through 2017 among 14,059 people with no prior TIA or stroke history, according to Vasileios-Arsenios Lioutas, MD, of Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, and colleagues.
The 435 people who had experienced a TIA had a subsequent stroke in nearly 30% of cases within 9 years their estimated 10-year cumulative stroke risk ended up being more than quadruple that of matched TIA-free controls (hazard 0.46 vs 0.09, adjusted HR 4.37, 95% CI 3.30-5.71), they reported online in